Protein Alignment HtrA2 and LOC110438948

DIOPT Version :9

• Sequence 1: NP_001262565.1
• Gene: HtrA2 / 41756
• FlyBaseID: FBgn0038233
• Length: 422
• Species: Drosophila melanogaster
• Sequence 2: XP_021328308.1
• Gene: LOC110438948 / 110438948
• -ID: -
• Length: 360
• Species: Danio rerio
• Alignment Length: 360
• Identity: 162/360 - (45%)
• Similarity: 242/360 - (67%)
• Gaps: 23/360 - (6%)

  Fly    69 VPFSLGA-------VVSAAIIQREDLTPTIAASKMTGRRRDFNFIADVVAGCADSVVYIEIKDTR 126
            ||.|.|:       |.:|.::.:..:     ..|:|........:.||......:.:.|.:|...
Zfish    13 VPISNGSGFRDGLIVTNAHVVNKHGV-----RVKLTNGETYNATVQDVDQAADIATIKINVKSKY 72

  Fly   127 HFDYFSGQPITASNGSGFIIEQNGLILTNAHVVINKPHTMVQVRLSDGRTFPATIEDVDQTSDLA 191
            :.....| ||  ||||||||..:|||:|||||| ||  ..|:|:|::|.|:.||::||||.:|:|
Zfish    73 NISLREG-PI--SNGSGFIISSDGLIVTNAHVV-NK--RGVRVKLTNGETYSATVQDVDQAADIA 131

  Fly   192 TLRIQVNN-LSVMRLGKSSTLRSGEWVVALGSPLALSNTVTAGVISSTQRASQELGLRNRDINYL 255
            |::|.|.| |..:||||||.:|.||:.|.:|||.:|.||:|:|::||.||.|:||||.|.:::|:
Zfish   132 TIKINVKNPLPTLRLGKSSDVRQGEFGVTMGSPFSLKNTITSGIVSSAQRGSKELGLSNSNMDYI 196

  Fly   256 QTDAAITFGNSGGPLVNLDGEAIGVNSMKVTAGISFAIPIDYVKVFLERAAEKRKKGSAYKTGYP 320
            ||||.|.|||:||||:|||||.||:|:||||||||||||.|.|::||:|:|:|:|  |.:.....
Zfish   197 QTDATIDFGNAGGPLINLDGEVIGINTMKVTAGISFAIPSDRVRLFLDRSADKQK--SWFGESGS 259

  Fly   321 VKRYMGITMLTLTPDILFELKSRSQNMPSNLTHGVLVWKVIVGSPAHSGGLQPGDIVTHINKKEI 385
            .:||:|:.||.|||.|:.||:.|..:.| :::||||:.:|||||||:..|::||.::..||..::
Zfish   260 KRRYIGVMMLILTPSIIEELRMRDPSFP-DVSHGVLIHRVIVGSPANRAGMKPGHVIIEINGVKV 323

  Fly   386 KNSSDVYDALADNSKTLDIVILRGVKQMHVTITPE 420
            ..|.::|:|:. .|::|::|:.||...:.:.:|||
Zfish   324 NMSEEIYNAVR-TSESLNVVVRRGADLLMLHMTPE 357

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HtrA2	NP_001262565.1	DegQ	67..422	CDD:223343	162/360 (45%)
		Trypsin_2	141..280	CDD:290102	82/139 (59%)
		PDZ_serine_protease	323..417	CDD:238487	37/93 (40%)
LOC110438948	XP_021328308.1	DegQ	84..>337	CDD:333159	137/259 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	176	1.000	Domainoid score	I3556
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	326	1.000	Inparanoid score	I2456
OMA	1	1.010	-	-		QHG59008
OrthoDB	1	1.010	-	-		D238833at33208
OrthoFinder	1	1.000	-	-		FOG0000153
OrthoInspector	1	1.000	-	-		otm25664
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22939
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X265
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	10	10.080