DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment HtrA2 and LOC110437830

DIOPT Version :9

Sequence 1:NP_001262565.1 Gene:HtrA2 / 41756 FlyBaseID:FBgn0038233 Length:422 Species:Drosophila melanogaster
Sequence 2:XP_021327998.1 Gene:LOC110437830 / 110437830 -ID:- Length:299 Species:Danio rerio


Alignment Length:307 Identity:152/307 - (49%)
Similarity:225/307 - (73%) Gaps:17/307 - (5%)


- Green bases have known domain annotations that are detailed below.


  Fly   118 VYIEIKDTRHFDYFSGQPITASNGSGFIIEQNGLILTNAHVVINKPHTMVQVRLSDGRTFPATIE 182
            :|...:..||  .|||:.:..||||||:|..:|||:||||||.||  ..|:|:|::|.|:.||::
Zfish     3 MYTSREAYRH--PFSGREVPISNGSGFVISSDGLIVTNAHVVANK--RGVRVKLTNGETYNATVQ 63

  Fly   183 DVDQTSDLATLRIQVNN-LSVMRLGKSSTLRSGEWVVALGSPLALSNTVTAGVISSTQRASQELG 246
            ||||.:|:||::|.|.| |..:|.||||.:|.||:|||:|||.:|.||:|:|::||.||.|:|||
Zfish    64 DVDQAADIATIKINVMNLLPTLRFGKSSDVRQGEFVVAMGSPFSLKNTITSGIVSSAQRDSKELG 128

  Fly   247 LRNRDINYLQTDAAITFGNSGGPLVNLDGEAIGVNSMKVTAGISFAIPIDYVKVFLERAAEKR-- 309
            |.|..::|:||||.|.||||||||:|||||.||:|:||||||||||||.|.|::||:|:.::.  
Zfish   129 LSNSSMDYIQTDATIDFGNSGGPLINLDGEVIGINTMKVTAGISFAIPSDRVRLFLDRSVDRSWF 193

  Fly   310 -KKGSAYKTGYPVKRYMGITMLTLTPDILFELKSRSQNMPSNLTHGVLVWKVIVGSPAHSGGLQP 373
             :.||.       :||:|:.||||||.|:.||:.|..:.| :::||||:.:|||||||:..|::|
Zfish   194 GESGSK-------RRYIGVMMLTLTPSIIEELRMRDPSFP-DVSHGVLIHRVIVGSPANRAGMKP 250

  Fly   374 GDIVTHINKKEIKNSSDVYDALADNSKTLDIVILRGVKQMHVTITPE 420
            |:::..||..::..|.::|:|:. .|::|::::.||...:.:.:|||
Zfish   251 GEVIIEINGVKVNTSEEIYNAVR-TSESLNVLVRRGADLLMLHMTPE 296

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
HtrA2NP_001262565.1 DegQ 67..422 CDD:223343 152/307 (50%)
Trypsin_2 141..280 CDD:290102 83/139 (60%)
PDZ_serine_protease 323..417 CDD:238487 37/93 (40%)
LOC110437830XP_021327998.1 DegQ 13..>285 CDD:333159 144/282 (51%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D238833at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
11.010

Return to query results.
Submit another query.