Protein Alignment HtrA2 and htra3

DIOPT Version :10

• Sequence 1: NP_650366.1
• Gene: HtrA2 / 41756
• FlyBaseID: FBgn0038233
• Length: 422
• Species: Drosophila melanogaster
• Sequence 2: XP_002938688.1
• Gene: htra3 / 100492341
• XenbaseID: XB-GENE-991914
• Length: 464
• Species: Xenopus tropicalis
• Alignment Length: 346
• Identity: 64/346 - (18%)
• Similarity: 101/346 - (29%)
• Gaps: 149/346 - (43%)

  Fly   927 VAGVTNLNGN----FSNYAADETSCQIQIEQAMLGAVLLSERRSSVW------------------ 969
            |.|...::|.    :||....|:||.:......|....:..:|||..
 Frog   523 VFGSDRISGKVARAYSNLRLKESSCPLLTRFFKLQFYYVPVKRSSSSPNAPLTNAESPLKSPSPS 587

  Fly   970 -------VFADSDGPNDLS-YVQLFDVSQQYQLSLNLVGV----GSSIC---TTPENNG----QF 1015
                   :|.|....||:| |:.:.|  ..|:  .|::|:    .|.:|   :.|||..    ..
 Frog   588 GRSPLEDIFGDEGSTNDISHYIGILD--PWYK--RNIMGLMDLSTSMLCQKSSKPENEATETTTM 648

  Fly  1016 P-------YYLRSLSQTTLGDIYMTD--------------------------------------- 1034
            |       ||.|..:::.|..:|..:
 Frog   649 PILADMVLYYCRFATRSLLLQLYQAEITFDGGGKQTEVFIQCLELGHSAALRAIRASGPGCKRLG 713

  Fly  1035 ---KLDQIMLFIVSMY-KSAVSHRYYVPD----CTS-----ATSYYMPVDGWTQSLTLAVTGTDL 1086
               ..|.|...:..:| ||:||.|....:    |||     |.:.|..:|..|:.|.|.|.
 Frog   714 IDGDRDAIPFTLQIVYSKSSVSGRSRWSNGEKVCTSVSLRKACTTYQELDSKTECLNLTVR---- 774

  Fly  1087 YSVEVTFPDGQKGQNSDYEL---------------------VAINDPETKLNQYVAACSGS---- 1126
               ||......|.:.|..::                     :.::..|.|:.|.|..|..|
 Frog   775 ---EVVKRQNSKTKKSFNQICTSHIKIDKAQIIAQHGGTFPLCLDQDERKILQRVIKCEVSPCYK 836

  Fly  1127 -------------FWNHRQQN 1134
                         .|:...||
 Frog   837 PEGRDFCRRNRPPSWSQASQN 857

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HtrA2	NP_650366.1	DegQ	141..421	CDD:440035
htra3	XP_002938688.1	IGFBP	25..76	CDD:459717
		Kazal_2	89..134	CDD:400135
		DegQ	181..454	CDD:440035