DRSC/TRiP Functional Genomics Resources

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Protein Alignment HtrA2 and LOC100149563

DIOPT Version :9

Sequence 1:NP_001262565.1 Gene:HtrA2 / 41756 FlyBaseID:FBgn0038233 Length:422 Species:Drosophila melanogaster
Sequence 2:NP_001122292.1 Gene:LOC100149563 / 100149563 -ID:- Length:195 Species:Danio rerio


Alignment Length:201 Identity:100/201 - (49%)
Similarity:151/201 - (75%) Gaps:9/201 - (4%)


- Green bases have known domain annotations that are detailed below.


  Fly   220 LGSPLALSNTVTAGVISSTQRASQELGLRNRDINYLQTDAAITFGNSGGPLVNLDGEAIGVNSMK 284
            :|||.:|.||:|:|::||.||.|:||||.|.:::|:||||.|.||||||||:|||||.||:|:||
Zfish     1 MGSPFSLKNTITSGIVSSAQRGSKELGLSNSNMDYIQTDATIDFGNSGGPLINLDGEVIGINTMK 65

  Fly   285 VTAGISFAIPIDYVKVFLERAAEKRKKGSAYKTGYPVKRYMGITMLTLTPDILFELKSRSQNMPS 349
            |||||||||     ::||:|:|:|:|  |.:......:||:|:.||||||.|:.||:.|..:.| 
Zfish    66 VTAGISFAI-----RLFLDRSADKQK--SWFGESGSKRRYIGVMMLTLTPSIIEELRMRDPSFP- 122

  Fly   350 NLTHGVLVWKVIVGSPAHSGGLQPGDIVTHINKKEIKNSSDVYDALADNSKTLDIVILRGVKQMH 414
            :::||||:.:|||||||:..|::|||::..||..::..|.::|:|:. .|::|::|:.||...:.
Zfish   123 DVSHGVLIHRVIVGSPANRAGMKPGDVIIEINGVKVNTSEEIYNAVR-TSESLNVVVRRGADLLM 186

  Fly   415 VTITPE 420
            :.:|||
Zfish   187 LHMTPE 192

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
HtrA2NP_001262565.1 DegQ 67..422 CDD:223343 100/201 (50%)
Trypsin_2 141..280 CDD:290102 38/59 (64%)
PDZ_serine_protease 323..417 CDD:238487 39/93 (42%)
LOC100149563NP_001122292.1 Trypsin_2 <1..61 CDD:290102 38/59 (64%)
PDZ_serine_protease 97..181 CDD:238487 37/85 (44%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C170579605
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0265
Hieranoid 00.000 Not matched by this tool.
Homologene 1 1.000 - - H113300
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
ZFIN 00.000 Not matched by this tool.
43.790

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