Protein Alignment HtrA2 and si:busm1-sl7.7

DIOPT Version :9

• Sequence 1: NP_001262565.1
• Gene: HtrA2 / 41756
• FlyBaseID: FBgn0038233
• Length: 422
• Species: Drosophila melanogaster
• Sequence 2: XP_021336609.1
• Gene: si:busm1-sl7.7 / 100034638
• ZFINID: ZDB-GENE-041001-38
• Length: 329
• Species: Danio rerio
• Alignment Length: 326
• Identity: 166/326 - (50%)
• Similarity: 235/326 - (72%)
• Gaps: 19/326 - (5%)

  Fly   103 FNFIADVVAG----CADSVVYIEIKDTRHFDYFSGQPITASNGSGFIIEQNGLILTNAHVVINKP 163
            |.|.|.|..|    |...|..|.:...||  .|||:....||||||||..:|||:||||||.||
Zfish    12 FFFFATVFVGGAGLCLGIVTNITLFLFRH--PFSGREGPISNGSGFIISSDGLIVTNAHVVANK- 73

  Fly   164 HTMVQVRLSDGRTFPATIEDVDQTSDLATLRIQVNN-LSVMRLGKSSTLRSGEWVVALGSPLALS 227
             ..|:|:|::|.|:.||::||||.:|:||::|.|.| |..:||||||.:|.||:|||:|||.:|.
Zfish    74 -RGVRVKLTNGETYNATVQDVDQVADIATIKINVKNPLPTLRLGKSSDVRQGEFVVAMGSPFSLK 137

  Fly   228 NTVTAGVISSTQRASQELGLRNRDINYLQTDAAITFGNSGGPLVNLDGEAIGVNSMKVTAGISFA 292
            ||:|:|::||.||.|:||||.|.:::|:||||.|.||||||||:|||||.||:|:||||||||||
Zfish   138 NTITSGIVSSAQRGSKELGLSNSNMDYIQTDATIDFGNSGGPLINLDGEVIGINTMKVTAGISFA 202

  Fly   293 IPIDYVKVFLERAAEKRKK---GSAYKTGYPVKRYMGITMLTLTPDILFELKSRSQNMPSNLTHG 354
            ||.|.|::||:|:|:|:|.   .|.:|     :||:|:.||||||.|:.||:.|..:.| :::||
Zfish   203 IPSDRVRLFLDRSADKQKSWFGESGWK-----RRYIGVMMLTLTPSIIEELRMRDPSFP-DVSHG 261

  Fly   355 VLVWKVIVGSPAHSGGLQPGDIVTHINKKEIKNSSDVYDALADNSKTLDIVILRGVKQMHVTITP 419
            ||:.:|||||||:..|::|||::..||..::..|.::|:|:. .|::|::|:.||...:.:.:||
Zfish   262 VLIHRVIVGSPANRAGMKPGDVIIEINGVKVNTSEEIYNAVR-TSESLNVVVRRGADLLMLHMTP 325

  Fly   420 E 420
            |
Zfish   326 E 326

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HtrA2	NP_001262565.1	DegQ	67..422	CDD:223343	166/326 (51%)
		Trypsin_2	141..280	CDD:290102	85/139 (61%)
		PDZ_serine_protease	323..417	CDD:238487	39/93 (42%)
si:busm1-sl7.7	XP_021336609.1	DegQ	41..>306	CDD:333159	148/273 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	70	1.000	Domainoid score	I9474
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H113300
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D238833at33208
OrthoFinder	1	1.000	-	-		FOG0000153
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.920