Protein Alignment cv-c and arhgap28

DIOPT Version :10

• Sequence 1: NP_001097786.1
• Gene: cv-c / 41749
• FlyBaseID: FBgn0285955
• Length: 2351
• Species: Drosophila melanogaster
• Sequence 2: NP_001007436.1
• Gene: arhgap28 / 492794
• ZFINID: ZDB-GENE-041114-147
• Length: 638
• Species: Danio rerio
• Alignment Length: 830
• Identity: 169/830 - (20%)
• Similarity: 279/830 - (33%)
• Gaps: 304/830 - (36%)

  Fly  1382 VEACKWLRAAGFPQYAQMYEDHQFPIDLNNVAKDHTNLENDQLQSLYRRLCVLNRCATMRLDQSH 1446
            |:.|..:....|..:....:|.|          .||..:|.:.|  ::.:..::.|.      ..
Zfish     3 VQDCGGVILTAFHSFRTHADDEQ----------KHTAADNRKAQ--HQPIVSMSVCG------PG 49

  Fly  1447 KPQTPQQKEESDDENFALSEHWTFQPHIRRWSRIGEMGLELPPPGLLSLNVEKTESSSKESSPDR 1511
            .|.:|:|....|    ::.::|:...:|:..:...:.              |..|.:|.:.:  .
Zfish    50 APASPEQCVSRD----SMEDYWSEVKNIQEDTHTHQQ--------------EPAEQASTDEA--E 94

  Fly  1512 FEE---DGAGITLVTPGCSKAGGIPNDGSSLGEGSDSGRLRRSGSERIKDQAKALLRRVESIKSR 1573
            .||   ..||:|.:..|..            |:|.....|    |.....||..:.:|:::....
Zfish    95 LEEAWLQDAGLTTLITGAQ------------GDGPTEALL----STLTHSQAAMVKKRLDNYTHT 143

  Fly  1574 RRKRQNRENVVISGPTVLDLSQFGQRSSLRKPDAVYSTP-PSPSALSPM----HTFPKAPFFGND 1633
            .||: ||:      ||             |....|:||| |:....||:    ...||.| ..|.
Zfish   144 LRKK-NRQ------PT-------------RHVRDVFSTPEPASELTSPVSPNGEISPKPP-QSNP 187

  Fly  1634 LKVPSHSDNFLSPNRSSPKRTPTTPRSMRTSPLHFFSSPMSQLKEGKSDDSSSYYSDSQESSTGG 1698
            .|.|....:|.|   :..|.:.:|.|::..|    ||:|.|:                   .|.|
Zfish   188 PKAPPACPDFTS---ADSKGSSSTLRTIILS----FSTPYSE-------------------GTRG 226

  Fly  1699 KLSLRKPSKARRFLQRTGKVDDIGAHSDSECHQGRKLL---IKDANSNTTEVKVKKLTRGGSLNL 1760
            :..||:..:.|:..:                 :.|:||   :......||.|          ::|
Zfish   227 QQKLREMQECRKIRK-----------------EDRELLCFQVVKPRQGTTRV----------MDL 264

  Fly  1761 GKDPKKRDGFRSSSFRSRSTSRKEAKNDEDTAGATTNGGSKRQPVVRWHSFQMEERPNMIFRKCF 1825
            ..|..::.|:.|                  ....||..|          :..:|.|.|.:
Zfish   265 SSDDMRKIGYIS------------------LIELTTFYG----------NLGIELRRNRV----- 296

  Fly  1826 SKKIEPLQEDAGGMPFAAMSAGQLQIIRKLALVTLTGHMERYCPSHRSGWNWELPKFIKKIKMPD 1890
                         ||..|
Zfish   297 -------------MPVKA----------------------------------------------- 301

  Fly  1891 YKDKKVFGVPLLMILQRS-----GQTLPLAVRAAFRWLQLNALDQVGIFRKSGGKSRIMKLREQI 1950
             :|..:||||||.:||..     |..:||..:.....|:...|...||.|..|...|:.:||:::
Zfish   302 -RDTGIFGVPLLTLLQNDRKIYPGSRIPLFFKKLLAKLEQTGLQTEGILRVPGSAVRVKQLRQEL 365

  Fly  1951 EV--TDSTAECMDVFDLQQAY--DVADMLKQYFRELPESLLTTKMSETFVAIFQHLPAEVRLDAV 2011
            ::  .|      |.||..|.:  |.|.:||.:.||||..|||......|.|:.:....:.::.|:
Zfish   366 DLHFYD------DRFDWDQVHQNDAAALLKMFIRELPYPLLTKLNMPAFTALQRISSPKYQIQAL 424

  Fly  2012 QCAVLLLPDENREILYVLLEFLTIVAANSQQNQMTSNNLGVCLAQSIFHSSISTGSASVSASPRR 2076
            ...:::||:.||:.|..|||||..|.|..::|:|...|:.:.:|.::|               ..
Zfish   425 HLLIMILPEPNRDTLKALLEFLRKVVACEEKNRMNVWNVSMIVAPNLF---------------TY 474

  Fly  2077 KGKGSGMPDMKE-LAEAK-----ASHECL-----SFMIEHYKQIYTAAKEKLSKCNFSYMEESKP 2130
            .||.:...::|. ||.|:     .||:.|     .|:|...:::..||..|.|..:    |.||
Zfish   475 IGKNAKQEEVKSALAAAQIVCTLISHQDLLWTVPCFLINQVRKMNDAAMAKKSLSS----ERSK- 534

  Fly  2131 LPLEALGEGMQFHNWRGYLYECTSATIKEGREKTRGWFSINSLNDSSVDI 2180
                           ||.|          .|.|.|....:..|.|..:.:
Zfish   535 ---------------RGLL----------SRWKDRERSEVKDLRDGVIRV 559

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cv-c	NP_001097786.1	SAM_DLC1,2-like	1382..1441	CDD:188937	10/58 (17%)
		RhoGAP_DLC1	1893..2116	CDD:239840	70/242 (29%)
		SRPBCC	2148..2343	CDD:472699	6/33 (18%)
arhgap28	NP_001007436.1	RhoGAP_ARHGAP18	306..516	CDD:239856	67/230 (29%)