Protein Alignment cv-c and Arhgap28

DIOPT Version :9

• Sequence 1: NP_001097786.1
• Gene: cv-c / 41749
• FlyBaseID: FBgn0285955
• Length: 2351
• Species: Drosophila melanogaster
• Sequence 2: XP_036016523.1
• Gene: Arhgap28 / 268970
• MGIID: 2147003
• Length: 756
• Species: Mus musculus
• Alignment Length: 604
• Identity: 139/604 - (23%)
• Similarity: 231/604 - (38%)
• Gaps: 127/604 - (21%)

  Fly  1618 LSPMHTFPKAPFFGNDLKVPSHSDNFLSPNRSSPKRTPTTPRSMRTSPLH--FFSSPMSQLKEGK 1680
            |:..|:..::...|.:.:..|.:.:.||  |.|..|.....|.:....||  .||...||.....
Mouse    68 LTAYHSHARSQPQGAEPRCASRASHPLS--RKSIPRCRRINRMLSNESLHPPSFSRSNSQASVDS 130

  Fly  1681 SDDSSSYYSDSQ---ESSTGGKLSLRKPSKARRFLQRTGKVD----------DIGAH---SDSEC 1729
            |.....:..:.:   |||.|.  |..:|..|.........||          |:|..   |.:|.
Mouse   131 SASMEEFLREIESIKESSVGA--SQEQPPTAAAAAAEVKPVDEGELEAEWLQDVGLSTLISGNEE 193

  Fly  1730 HQGRKLLIKDANSNTTEVKVKKLTRGGSLNLGKDPKK-----RDGF-----RSSSFRSRSTSRKE 1784
            ..|:.||  ...:.|....|||.....:..|.|..|:     ||.|     ..|.....:|....
Mouse   194 EDGKALL--STLTRTQAAAVKKRYNTYTQTLRKKNKQPVRDVRDIFGVSESPPSDSCEHATQLDG 256

  Fly  1785 AKNDEDTAGAT------------------TNGGSKRQPVVR-------WHSFQM-EERPNMIFRK 1823
            .|.::|..|.|                  |||.:..:..|:       :|...: .|...:.|..
Mouse   257 TKEEKDLPGVTKTSRPLSILEAIPDIAVHTNGSADAEQSVQSTLSDDDYHGKNVPAEAEELSFEV 321

  Fly  1824 CFS------------KKIEPLQED-------AGGMPFAAMSAGQLQI-----IRKLALVTLTGHM 1864
            .:|            ||.:..:||       .....|.....|.|.:     ||.|:|:.||...
Mouse   322 SYSEMVTEMPDRNKWKKSDIKKEDYVLTKFIIQKTRFGLTETGDLSVEDMKKIRHLSLIELTAFF 386

  Fly  1865 ERYCPSHRSGWNWELPKFIKKIKMPDYKDKKVFGVPLLMILQRSGQ-----TLPLAVRAAFRWLQ 1924
            :.:        ..:|.:  .|.:....:|..:|||||.::|....:     .:||.::..|:.::
Mouse   387 DAF--------GIQLKR--NKTERVRGRDNGIFGVPLTVLLDNDRKKDPAVKVPLVLQKFFQKVE 441

  Fly  1925 LNALDQVGIFRKSGGKSRIMKLREQIEVTDSTAECMDVF--DLQQAYDVADMLKQYFRELPESLL 1987
            .:.|:..||||.||..:::.:.||:::...:.    |.|  |.....:.|.|||.:|||||.||.
Mouse   442 ESGLESEGIFRLSGCTAKVKQYREELDARFNA----DKFKWDKMCHREAAVMLKAFFRELPTSLF 502

  Fly  1988 TTKMSETFVAIFQHLP-AEVRLDAVQCAVLLLPDENREILYVLLEFLTIVAANSQQNQMTSNNLG 2051
            ..:....|:::.:..| .:|:..|:...|:.|||.||:....|:.|...|.||..:|:|...|:.
Mouse   503 PVEYIPAFISLMERGPDIKVQFQALHLMVMALPDANRDTAQALMAFFNKVIANESKNRMNLWNIS 567

  Fly  2052 VCLAQSIFHSSISTGSASVSASPRRKGKGSGMPDMKELAEAKASHECLSFMIEHYKQIYTAAK-- 2114
            ..:|.::|.|               :.|.|   |.:||..|..:...:..|:::.|.::....
Mouse   568 TVMAPNLFFS---------------RSKHS---DCEELLLANTATHIIRLMLKYQKILWKVPSFL 614

  Fly  2115 -EKLSKCNFSYMEESKPLP 2132
             .::.:.|.:.|...|.||
Mouse   615 ITQVRRMNEATMLLKKQLP 633

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cv-c	NP_001097786.1	SAM_DLC1,2-like	1382..1441	CDD:188937
		RhoGAP_DLC1	1893..2116	CDD:239840	62/233 (27%)
		SRPBCC	2148..2343	CDD:301327
Arhgap28	XP_036016523.1	RhoGAP_ARHGAP18	408..619	CDD:239856	61/232 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2200
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810