Protein Alignment NK7.1 and LBX2

DIOPT Version :10

• Sequence 1: NP_650357.2
• Gene: NK7.1 / 41747
• FlyBaseID: FBgn0024321
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_001269359.1
• Gene: LBX2 / 85474
• HGNCID: 15525
• Length: 198
• Species: Homo sapiens
• Alignment Length: 180
• Identity: 50/180 - (27%)
• Similarity: 77/180 - (42%)
• Gaps: 23/180 - (12%)

  Fly   317 SSGKPAAKKKKLSSTVALPPDISPTGSSDSLMRDKLMANNSSSPG-SNVNAQMQSNANST----- 375
            |..:|...:..||....|.|.:.|...|...:.:       |.|| ::....::...:.|
Human     3 SGREPRTPRTLLSIADILAPRMVPRAPSAPQLPE-------SGPGPTSPLCALEELTSKTFRGLD 60

  Fly   376 ---LETTE----DDSDSGSTDARRKKKARTTFTGRQIFELEKMFENKKYLSASERTEMAKLLMVT 433
               |:.:|    .|:.......|:::|:||.||.:|:.|||:.|..:|||:.|||..:|..|.:.
Human    61 ARALQPSEGRAGPDALGPGPFGRKRRKSRTAFTAQQVLELERRFVFQKYLAPSERDGLATRLGLA 125

  Fly   434 ETQVKIWFQNRRTKWKKQDNVTNNEAAEHKSSNAKPGATGTATTTPSGEP 483
            ..||..||||||.|.|:.   .....|:..|..|.......:...|.|.|
Human   126 NAQVVTWFQNRRAKLKRD---VEEMRADVASLRALSPEVLCSLALPEGAP 172

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NK7.1	NP_650357.2	Homeodomain	394..450	CDD:459649	27/55 (49%)
LBX2	NP_001269359.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	24..46		5/28 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	63..89		5/25 (20%)
		Homeodomain	86..142	CDD:459649	27/55 (49%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	173..198		50/180 (28%)