Protein Alignment NK7.1 and Nkx6-1

DIOPT Version :9

• Sequence 1: NP_001247103.1
• Gene: NK7.1 / 41747
• FlyBaseID: FBgn0024321
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_113925.1
• Gene: Nkx6-1 / 65193
• RGDID: 69318
• Length: 365
• Species: Rattus norvegicus
• Alignment Length: 449
• Identity: 127/449 - (28%)
• Similarity: 173/449 - (38%)
• Gaps: 106/449 - (23%)

  Fly   105 MLRV--RDNNNMASTISDSPPTTFLQKQLEAVVAPRPSSVHPQHQQPQQQTVQLQQQRRSVSTPA 167
            ||.|  .:....::.:..|||...|....|......|::..|....|..          |.|:.:
  Rat     1 MLAVGAMEGPRQSAFLLSSPPLAALHSMAEMKTPLYPAAYPPLPTGPPS----------SSSSSS 55

  Fly   168 ITTTPGPPTNWH---------AHVYDRL--PPH----PTPHSIADILGMSFVKKERPE--VAFDA 215
            .:::|.||...|         |.....|  ||.    .|||.|.|||       .||.  ||..|
  Rat    56 SSSSPSPPLGAHNPGGLKPPAAGGLSSLGSPPQQLSAATPHGINDIL-------SRPSMPVASGA 113

  Fly   216 QGPAKSPNSILKPYQEQQPIRSSSISMSDASEEESAAVAGATSAATAAAAVAATITAATVATPLD 280
            ..|:.||:.            |||.|.|.||         ||||:.||||.||...||.     .
  Rat   114 ALPSASPSG------------SSSSSSSSAS---------ATSASAAAAAAAAAAAAAA-----S 152

  Fly   281 QPLNLCVVKKSRDSNNSPMPATKQSQILGKSATKKESSGKPAAKKKKLSSTVALPPDISPTGSSD 345
            .|..| :....|.|:.|| |..........||....:.|:   ..|.|:......|...|
  Rat   153 SPAGL-LAGLPRFSSLSP-PPPPPGLYFSPSAAAVAAVGR---YPKPLAELPGRTPIFWP----- 207

  Fly   346 SLMRDKLMANNSSSPGSNVNAQMQSNANSTLETTEDDSDSGSTDARRKKKARTTFTGRQIFELEK 410
            .:|:        |.|..:.......:..|.|.    |.|.      ::|..|.||:|:|||.|||
  Rat   208 GVMQ--------SPPWRDARLACTPHQGSILL----DKDG------KRKHTRPTFSGQQIFALEK 254

  Fly   411 MFENKKYLSASERTEMAKLLMVTETQVKIWFQNRRTKWKKQDNVTNNEAAEHKSSNAKPGA-TGT 474
            .||..|||:..||..:|..|.:||:|||:|||||||||:|:      .|||..::..|..: |..
  Rat   255 TFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKK------HAAEMATAKKKQDSETER 313

  Fly   475 ATTTPSGEPTDKRSSNATSPTVGNAATIAEIKKSPKSPNRGSNNNNNNTLNNNVNNSEG 533
            ...|...|..|...:....|. .:...|.::.|..||        :..:|..:.:.:||
  Rat   314 LKGTSENEEDDDDYNKPLDPN-SDDEKITQLLKKHKS--------SGGSLLLHASEAEG 363

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NK7.1	NP_001247103.1	Homeobox	397..449	CDD:278475	32/51 (63%)
Nkx6-1	NP_113925.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	35..136		37/138 (27%)
		Repressor domain. /evidence=ECO:0000250	102..269		67/227 (30%)
		Homeobox	240..294	CDD:395001	33/53 (62%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	295..365		16/84 (19%)
		Involved in DNA-binding. /evidence=ECO:0000250	307..365		12/66 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166336909
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840