Protein Alignment NK7.1 and NKX3-2

DIOPT Version :10

• Sequence 1: NP_650357.2
• Gene: NK7.1 / 41747
• FlyBaseID: FBgn0024321
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_001180.1
• Gene: NKX3-2 / 579
• HGNCID: 951
• Length: 333
• Species: Homo sapiens
• Alignment Length: 293
• Identity: 75/293 - (25%)
• Similarity: 123/293 - (41%)
• Gaps: 70/293 - (23%)

  Fly   191 TPHSIADILGMSFVKKERPEVAFDAQGPAKSPNSILKPYQEQQPIRSSSISMSDA-------SEE 248
            |..||..||..   |:||..:|.....||....             ::|::.:.|       .|.
Human    10 TSFSIQAILNK---KEERGGLAAPEGRPAPGGT-------------AASVAAAPAVCCWRLFGER 58

  Fly   249 ESAAVAGATSAATAAAAVAATITAATVATPLDQPLNLCVVKKSRDSNNSPMPATKQSQILGKSAT 313
            ::.|:.||..:..|:.|...|....|..:|           :..||:::   .:::::...:.|.
Human    59 DAGALGGAEDSLLASPAGTRTAAGRTAESP-----------EGWDSDSA---LSEENESRRRCAD 109

  Fly   314 KKESS-----------GKPA---AKKKKLSSTVALPPDISPTGSSDSLMRDKLMANNS------- 357
            .:.:|           |:|.   |..|.|....|        |.|||.|...:..:.|
Human   110 ARGASGAGLAGGSLSLGQPVCELAASKDLEEEAA--------GRSDSEMSASVSGDRSPRTEDDG 166

  Fly   358 -SSPGSNVNAQMQ---SNANSTLETTEDDSDSGSTDARRKKKARTTFTGRQIFELEKMFENKKYL 418
             ...|::|:|...   ....|......::.:..:....|||::|..|:..|:||||:.|.:::||
Human   167 VGPRGAHVSALCSGAGGGGGSGPAGVAEEEEEPAAPKPRKKRSRAAFSHAQVFELERRFNHQRYL 231

  Fly   419 SASERTEMAKLLMVTETQVKIWFQNRRTKWKKQ 451
            |..||.::|..|.:|||||||||||||.|.|::
Human   232 SGPERADLAASLKLTETQVKIWFQNRRYKTKRR 264

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NK7.1	NP_650357.2	Homeodomain	394..450	CDD:459649	30/55 (55%)
NKX3-2	NP_001180.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	65..113		10/61 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	138..212		16/81 (20%)
		Homeodomain	207..263	CDD:459649	30/55 (55%)