Protein Alignment NK7.1 and BARHL1

DIOPT Version :10

• Sequence 1: NP_650357.2
• Gene: NK7.1 / 41747
• FlyBaseID: FBgn0024321
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_064448.1
• Gene: BARHL1 / 56751
• HGNCID: 953
• Length: 327
• Species: Homo sapiens
• Alignment Length: 272
• Identity: 81/272 - (29%)
• Similarity: 115/272 - (42%)
• Gaps: 61/272 - (22%)

  Fly   272 AATVATPLDQPL------NLCVVKKSRDSNNSPMPATKQSQILGKSATKKESSGKPAAKKKKLSS 330
            |.:.|.|...||      .|.:..:|..|::...||:.....|.....:...:..|.........
Human    17 AGSPALPKGDPLLGDCRSPLELSPRSESSSDCSSPASPGRDCLETGTPRPGGASGPGLDSHLQPG 81

  Fly   331 TVALPPDISPTGSSDSLMRDKL--------MANNSSS-------PGSNVNAQMQ----------- 369
            .::.|.. |.|.:|..|:||.|        .|..|||       ||..:.|:..
Human    82 QLSAPAQ-SRTVTSSFLIRDILADCKPLAACAPYSSSGQPAAPEPGGRLAAKAAEDFRDKLDKSG 145

  Fly   370 SNANSTLE-TTEDDSD---SGSTDA-----RRKKKARTTFTGRQIFELEKMFENKKYLSASERTE 425
            |||:|..| ..:::.|   |.|.|:     ::.:||||.||..|:.:||:.||.:||||..:|.|
Human   146 SNASSDSEYKVKEEGDREISSSRDSPPVRLKKPRKARTAFTDHQLAQLERSFERQKYLSVQDRME 210

  Fly   426 MAKLLMVTETQVKIWFQNRRTKWKKQDNV-------TNNEAAEHKS------------SNAKPGA 471
            :|..|.:|:||||.|:||||||||:|..|       ..|.:|..:.            ||..|||
Human   211 LAASLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPSPYFYPQSLVSNLDPGA 275

  Fly   472 TGTATTTPSGEP 483
            .......||..|
Human   276 ALYLYRGPSAPP 287

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NK7.1	NP_650357.2	Homeodomain	394..450	CDD:459649	32/55 (58%)
BARHL1	NP_064448.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..90		13/73 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	112..184		19/71 (27%)
		Homeodomain	179..235	CDD:459649	32/55 (58%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	305..327