Protein Alignment NK7.1 and E5

DIOPT Version :10

• Sequence 1: NP_650357.2
• Gene: NK7.1 / 41747
• FlyBaseID: FBgn0024321
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_524825.1
• Gene: E5 / 45396
• FlyBaseID: FBgn0008646
• Length: 524
• Species: Drosophila melanogaster
• Alignment Length: 619
• Identity: 119/619 - (19%)
• Similarity: 219/619 - (35%)
• Gaps: 163/619 - (26%)

  Fly    80 LTIPPTSMTTHMVSP-IGNSKEKLVNMLRVRDNNNMASTISDSPPTTFLQKQLEAVVAPRPSSVH 143
            |.:.||       || :.:|.....:...|..::.::::.|..|...|   .::::|.
  Fly    12 LPMAPT-------SPFVSSSSSVAASSTSVSASSTVSASASSKPKLAF---SIDSIVG------- 59

  Fly   144 PQHQQPQQQTVQLQQQRRSV--STPAITTTPGPPTNWHAHVYDRLPPHPTPHSIADILGMSFVKK 206
                   :.:.:....|.||  |.|..:.:|..|||.:.      ....||.        .::..
  Fly    60 -------ESSTRSAPLRVSVISSPPPRSESPASPTNTNN------SGRRTPR--------GYIYC 103

  Fly   207 ERPEVAFDAQGPAKSPNSILKPYQEQQPIRSSSISMSDASEEESAAVAGATSAATAAAAVAATIT 271
            .|.:....::.|.:||                 :|.|.:........|.|.:.|.:....:.|..
  Fly   104 RRRDSLDRSRSPQRSP-----------------VSRSPSPPNAGGNPAAAGNTAKSGDPSSGTGN 151

  Fly   272 AATVATPLDQPL-NLCVVKKSRDSNNS--------PMPATKQSQILG-----KSATKKESSGKPA 322
            ..|:..||..|. ||.:: .:|.|.|:        |.|.::....|.     .:|.......:..
  Fly   152 PPTLIRPLPLPAPNLALI-GNRTSPNAMAVRMAGPPHPPSQPPPFLAAQFQMAAALAHHHQQQQQ 215

  Fly   323 AKKKKLSSTVALPP-----------------------------DISPTGSSDSLMRDK------- 351
            .::::|......||                             ...|.||:..|:||.
  Fly   216 QQQQQLPPVPTGPPHGPHPHLPPGQIPLGIFPGGPHPGHPPPHGHHPFGSAPHLIRDSYPLYPWL 280

  Fly   352 LMANNSSSPGSNVNAQMQSNANSTLETTEDDSDSGSTDARRKKKARTTFTGRQIFELEKMFENKK 416
            |..:....|....|...|                   ..|:.|:.||.|:..|:.:||..||...
  Fly   281 LSRHGRIFPRFPGNFLFQ-------------------PFRKPKRVRTAFSPTQLLKLEHAFEGNH 326

  Fly   417 YLSASERTEMAKLLMVTETQVKIWFQNRRTKWKK--QDNVTNNEAAEHKSSNAKPGATGTATTTP 479
            |:..:||.::|:.|.:||||||:||||||||.|:  |:....::...:|.|::..|..|
  Fly   327 YVVGAERKQLAQGLSLTETQVKVWFQNRRTKHKRMQQEGGDGSDTKSNKGSSSGGGGGG------ 385

  Fly   480 SGEPTDKRSSNATSPTVGNAATIAEIKKSPKSPNRGSNNNNNNTLNNNVNNSEGKVPAKQSTTKI 544
            .||...|...:..|         .|..:.|:..:....::.:..::.:...||......|   ::
  Fly   386 DGEDDAKHDGSQHS---------YEDAEDPEDEDEIEEDDEDEVIDMDDYGSEMDAEEHQ---RL 438

  Fly   545 KKQLNALLEKTVKTANQ--AHRSAELESSDQKPAVEKRPNNSNENQLLHQRLHQHAIPLTVEPAA 607
            ::|....|.:..:...|  |..:|.|....|...:::...:..:.   |.:..||.|
  Fly   439 REQFQQQLAQHQQQFMQQNAGEAATLSPQQQHQLLQQHQQHLQQQ---HHQQQQHFI-------- 492

  Fly   608 PLEQTEKLDIKREESPQHRELQLSLQRAAIQNGQ 641
              :|.::|.::..|..:.||.:...:::..:..|
  Fly   493 --QQQQQLYLREREREREREREREREKSRERENQ 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NK7.1	NP_650357.2	Homeodomain	394..450	CDD:459649	28/55 (51%)
E5	NP_524825.1	Homeodomain	304..360	CDD:459649	28/55 (51%)