Protein Alignment NK7.1 and MSX1

DIOPT Version :10

• Sequence 1: NP_650357.2
• Gene: NK7.1 / 41747
• FlyBaseID: FBgn0024321
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_002439.2
• Gene: MSX1 / 4487
• HGNCID: 7391
• Length: 303
• Species: Homo sapiens
• Alignment Length: 263
• Identity: 81/263 - (30%)
• Similarity: 102/263 - (38%)
• Gaps: 46/263 - (17%)

  Fly   248 EESA----AVAGATSAATAAAAVAATITA-ATVATPLDQP--LNLCVVKKSRDSNNSPMPATKQS 305
            |:||    |..||..|.:||||.||.:.| ...|.|...|  |...|.....|...   |..|:|
Human    17 EDSAFGKPAGGGAGQAPSAAAATAAAMGADEEGAKPKVSPSLLPFSVEALMADHRK---PGAKES 78

  Fly   306 --------QILGKSA----TKKESSGKPAAKKK-------KLSSTVALPPD-ISPTGSSDSLMRD 350
                    |..|.||    ....|.|.|.|...       .:...:.||.| :....|.:...|.
Human    79 ALAPSEGVQAAGGSAQPLGVPPGSLGAPDAPSSPRPLGHFSVGGLLKLPEDALVKAESPEKPERT 143

  Fly   351 KLMANNSSSPGSNVNAQMQSNANSTLETTEDDSDSGSTDARRKKKARTTFTGRQIFELEKMFENK 415
            ..|.:...||..   |:..|....||.           ..:..:|.||.||..|:..||:.|..|
Human   144 PWMQSPRFSPPP---ARRLSPPACTLR-----------KHKTNRKPRTPFTTAQLLALERKFRQK 194

  Fly   416 KYLSASERTEMAKLLMVTETQVKIWFQNRRTKWKKQDNVTNNEAAEHKSSNAKPGATGTATTTPS 480
            :|||.:||.|.:..|.:|||||||||||||.|.|:.......:..........|.|.|  .:.|.
Human   195 QYLSIAERAEFSSSLSLTETQVKIWFQNRRAKAKRLQEAELEKLKMAAKPMLPPAAFG--LSFPL 257

  Fly   481 GEP 483
            |.|
Human   258 GGP 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NK7.1	NP_650357.2	Homeodomain	394..450	CDD:459649	31/55 (56%)
MSX1	NP_002439.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	18..55		15/36 (42%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	69..117		12/50 (24%)
		PTZ00449	<105..>248	CDD:185628	46/156 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	133..174		9/54 (17%)
		Homeodomain	173..229	CDD:459649	31/55 (56%)