Protein Alignment NK7.1 and Hmx

DIOPT Version :10

• Sequence 1: NP_650357.2
• Gene: NK7.1 / 41747
• FlyBaseID: FBgn0024321
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_001262674.1
• Gene: Hmx / 42110
• FlyBaseID: FBgn0264005
• Length: 718
• Species: Drosophila melanogaster
• Alignment Length: 769
• Identity: 163/769 - (21%)
• Similarity: 259/769 - (33%)
• Gaps: 248/769 - (32%)

  Fly    10 HLEAAEMAS--GALAHNYGIVKDQQQQQQQQQQLHHLQQQHHHQQQQQQQQQQQSNSDLYKMACN 72
            ||..|..|:  ..|.|.......|||||.|.||.|  ||.|..:.....:..:::..|..:....
  Fly   113 HLHPAHGATHPALLQHALTPTGQQQQQQLQVQQQH--QQSHVERLSPPMKSPERNGGDEVQGHSL 175

  Fly    73 GYNYSSPLTIPPTSMTTHMVSPIGNSKEKLVNMLRVRDNNN------------------------ 113
            ..|.|..|....|     ..|....:....|....:.:|:|
  Fly   176 NNNNSKALNHNNT-----CASAAAAAAAAAVAAANLSNNSNDSNGSSGGGGGKSTTGSNGFTSFS 235

  Fly   114 MASTISDSPPTTFLQKQLEAVVAPRPSSVHPQHQQPQQQTVQ-----LQQQRRSVSTPAITTTPG 173
            ::|.:|.|.|..  :.....::.|.|....|....||...:.     :.|........|....||
  Fly   236 ISSILSRSEPAK--KNGAAGLITPIPQLPQPGAGGPQDAAMLSRLGFISQWGALAGRYAALCPPG 298

  Fly   174 PPTNWHAHVYDRLPPHPTPHSIADILGMSFVKKERPEVAFDAQGPAKSPNSILKPYQEQQPIRSS 238
            .|  |   ...|||.|...|.                        :.|.|:...|        .|
  Fly   299 WP--W---APQRLPFHSPTHD------------------------SSSTNTTENP--------PS 326

  Fly   239 SISMSDASEEESAAVAGATSAATAAAAVAATITAATVATPLDQPLNLCVVKKSRDSNNSPMPATK 303
            ..|||..:...::....:::.|:              .:|...||:...         .|:.:.:
  Fly   327 PTSMSPNNNNNNSNTTASSNQAS--------------KSPSHHPLHPLY---------HPLGSQQ 368

  Fly   304 QSQILGKSATKKESSGKPAAKKKKLSSTVALPPDISPTGSSDSLMRDKLMANNSSSPGSNVNAQM 368
            |.|...:.....:....|..::::.......|...|.:|...||....    :....||:....:
  Fly   369 QQQQQQQHQQHPQQQQHPQQQQQQHPHQPTTPTSSSSSGGGSSLTHHP----HPHLTGSHGGYLL 429

  Fly   369 QSNANSTLE-----TTEDDSDSGSTD---------ARRKKKARTTFTGRQIFELEKMFENKKYLS 419
            .|::|.:.|     ..|||...|.:|         ::||||.||.|:..|:|:||..|:.|:|||
  Fly   430 PSSSNESDEEGEEIIEEDDGTDGPSDSSSPHGDGNSKRKKKTRTVFSRAQVFQLESTFDLKRYLS 494

  Fly   420 ASERTEMAKLLMVTETQVKIWFQNRRTKWKKQDNVTNNEAAEHKSSNAKPGATGTATTTPSGEPT 484
            :|||..:|..|.:|||||||||||||.|||:|      .|||.:::|
  Fly   495 SSERAGLAASLRLTETQVKIWFQNRRNKWKRQ------LAAELEAAN------------------ 535

  Fly   485 DKRSSNATSPTVGNAATIAE-IKKSPKSPNRGSNNNNNNTLNNNVNNSEGKVP------------ 536
                       :.|.|..|: :.:.|...:.|:              :.|.||
  Fly   536 -----------MANMAHAAQRLVRVPVLYHDGT--------------TAGFVPPPPPHHHPMQYY 575

  Fly   537 -AKQSTTKIKKQLNALLEKT--VKTANQAHRSAELESSDQKPAVEKRPNNSNENQLLHQRLHQHA 598
             |.::|:..:..|::|:...  :.||               |....:|.||    :.|
  Fly   576 AAARNTSPPRPPLSSLVXGVGCLATA---------------PMSLLKPPNS----MAH------- 614

  Fly   599 IPLTVEPAAPLEQTEKLDIKREESPQHRELQLSLQRAAIQNGQLTEMDFESKLAASKISIALAMA 663
             |...:|..|             :|.|.:     ||:.:...||||.|.:|
  Fly   615 -PPHPQPPPP-------------APLHMQ-----QRSFLGCEQLTETDMDS-------------- 646

  Fly   664 NKQMQPEKRVKTESSSSEGEGDGDGEEEEEEEEVSSSEHGDS---IEAHDSQDQ 714
            :.:.:....:..|.::.:.|.|   ||:|....|.|:....|   :|:.:|..|
  Fly   647 DSEQERSHMMDDEDAAIDVEAD---EEQESASPVPSATPPKSSLCLESKESGGQ 697

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NK7.1	NP_650357.2	Homeodomain	394..450	CDD:459649	34/55 (62%)
Hmx	NP_001262674.1	Homeodomain	469..525	CDD:459649	34/55 (62%)