DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NK7.1 and nkx1.2la

DIOPT Version :9

Sequence 1:	NP_001247103.1	Gene:	NK7.1 / 41747	FlyBaseID:	FBgn0024321	Length:	721	Species:	Drosophila melanogaster
Sequence 2:	NP_997995.2	Gene:	nkx1.2la / 405755	ZFINID:	ZDB-GENE-040615-1	Length:	270	Species:	Danio rerio

Alignment Length:	246	Identity:	62/246 - (25%)
Similarity:	95/246 - (38%)	Gaps:	81/246 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   315 KESSGKPAAKKKKLSSTV-ALPPDISPTGSSDSLMRDKLMANNSSSPGSNVNAQMQSNANSTLET 378
            :||.||..:..:...|.: .|.|....:..:|...:::..::.::..||...::...:::...|:
Zfish     5 QESGGKGTSDHRISFSIIDILDPTKFTSKKTDVSEKERTSSSENTGFGSLEESRNGKHSDGECES 69

  Fly   379 TEDDSD---------------------------SG----------------------STDARRK- 393
            |.|.||                           ||                      |...||:
Zfish    70 TGDRSDDRHGCVRLHPPDPDVDFDCSSSHRSLKSGFSPCEDPDEAAEERMTPAPDDVSRQRRRRS 134

  Fly   394 -------KKARTTFTGRQIFELEKMFENKKYLSASERTEMAKLLMVTETQVKIWFQNRRTKWKKQ 451
                   ::|||.||..|:..||..|...:|||..||..:|..|.:|||||||||||||||||||
Zfish   135 DHSCAKPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQ 199

  Fly   452 DNVTNNEAAEHKSSNAKPGATGTATTTPSGEPTDKRSSNATSPTVGNAATI 502
            :                ||...:.....:..|.       .||:.|:|:.:
Zfish   200 N----------------PGVESSLQAGTNSLPN-------ISPSCGSASAL 227

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NK7.1	NP_001247103.1	Homeobox	397..449	CDD:278475	30/51 (59%)
nkx1.2la	NP_997995.2	Homeobox	145..197	CDD:278475	30/51 (59%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576038
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840