Protein Alignment NK7.1 and Dbx

DIOPT Version :10

• Sequence 1: NP_650357.2
• Gene: NK7.1 / 41747
• FlyBaseID: FBgn0024321
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_647677.2
• Gene: Dbx / 38254
• FlyBaseID: FBgn0261723
• Length: 741
• Species: Drosophila melanogaster
• Alignment Length: 741
• Identity: 151/741 - (20%)
• Similarity: 237/741 - (31%)
• Gaps: 262/741 - (35%)

  Fly    34 QQQQQQQLHHLQQQHHHQQQQQQQQQQQSNSDLYKMACNGYNYSSPLTIPPTSMTTHMVSPIGNS 98
            ||...||..|..||||.|||.....|.|      .:|..|:.:|.|        .:|.
  Fly   185 QQNFMQQHSHQYQQHHQQQQPHSHPQHQ------PLAVPGHQHSHP--------HSHH------- 228

  Fly    99 KEKLVNMLRVRDNNNMASTISDSPPTTFLQKQLEAVVAPRPSSVHPQHQQPQQQTVQLQQQRRSV 163
                      ..:::..:..:..|...||..||            |.||..|||. .:|||
  Fly   229 ----------HHHHHPGAGHAHFPHPAFLTHQL------------PPHQHHQQQQ-HVQQQ---- 266

  Fly   164 STPAITTTPGPPTNWHAHVYDRLPPHPTPHSIADILGMSFVKKERPEVAFDAQGPAKSPNSILKP 228
                                     ||         |.|.    :|:.|..:..|..
  Fly   267 -------------------------HP---------GNSC----QPQTASSSSSPGS-------- 285

  Fly   229 YQEQQPIRSSSISMSDASEEESAAVAGATSAATAAAAVAATITAATVATPLDQPLNLCVVKKSRD 293
                        ::||:.....|:.|....:.|..:...|            :|..|.......|
  Fly   286 ------------TISDSDNNHGASTANGNGSGTGNSGQDA------------RPHELANSNPDED 326

  Fly   294 SNNS---PMPATKQSQILGKSAT-----KKESSGKPAAKKKKLSSTVALPPDISPTGSSDSLMR- 349
            |:.|   .....:|.|:||...|     .....|.|..........:|.|....||......:.
  Fly   327 SSASRRLTQDKQQQQQLLGAGGTGGGGGGGHGHGHPTPPPPPPPPVIAKPMPSRPTPFLPHTLNH 391

  Fly   350 ---DKLMANNSSSPGSNVNAQMQSN--------ANSTLETTEDDSDSGSTDARRKKKARTTFTGR 403
               ..|:| :..:|..:|.||:...        |:||           ....||....|..|:..
  Fly   392 PHLHSLLA-HCRNPYMSVGAQVFPLPPGQGFPWAHST-----------RGKPRRGMMRRAVFSDS 444

  Fly   404 QIFELEKMFENKKYLSASERTEMAKLLMVTETQVKIWFQNRRTKWK-------------KQDNVT 455
            |...|||.|:.:||:|..:|.::|:.|.:.::||||||||||.||:             :...:.
  Fly   445 QRKGLEKRFQQQKYISKPDRKKLAERLGLKDSQVKIWFQNRRMKWRNSKERELLASGGSRDQTLP 509

  Fly   456 NNEAAEHKSSNAK-----------------------PGATG-----TATTTPSGEPTDKRSSNAT 492
            |........|:||                       |||..     ||..||.   :.:..|:.:
  Fly   510 NKNNPNPDLSDAKCDRPLTPLSPSLLSPNGSATPPPPGAVAKDEPPTAAVTPK---SPQSVSSRS 571

  Fly   493 SPTVGNAATIAEIKKSPKSPNRG--SNNNNNNTLNNNVNNSEGKVPAKQSTTKIKKQLNALLEKT 555
            ||:||....|:.......|...|  |.:.....|.....:|....|...:.::.:.::||.::|.
  Fly   572 SPSVGYGLQISSPPPLLTSLKMGDQSASATPTPLPGTTVSSAAASPPGVTASEFQAKINAEMQKQ 636

  Fly   556 VKTANQAHRSAELESSDQKPAVEKRPNNSNENQLLHQRLHQHAIPLTVEPAAPLEQTEKLDIKRE 620
            :..|:...:   ||:|.|: |.::|      .:.|.|:||
  Fly   637 LVAADLKFK---LENSIQE-AKQRR------FEQLQQQLH------------------------- 666

  Fly   621 ESPQH---RELQLSLQRAAIQNGQLTEMDFESKLAASKISIALAMANKQMQPEKRVKTESSSSEG 682
            .||..   ||::|:...||.|.....:.                  .:|.|.::..:.:.:..:.
  Fly   667 HSPHFSAMREVELAAAAAAAQLHHHHQQ------------------QQQQQQQQHAQQQHAQQQH 713

  Fly   683 EG----------DGDGEEEEEEEEVS 698
            :|          |.|....:.:||:|
  Fly   714 QGGSEFMKLYYDDYDDSNSDSDEEIS 739

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NK7.1	NP_650357.2	Homeodomain	394..450	CDD:459649	25/68 (37%)
Dbx	NP_647677.2	Homeodomain	437..491	CDD:459649	25/53 (47%)