Protein Alignment NK7.1 and Nkx2-4

DIOPT Version :10

• Sequence 1: NP_650357.2
• Gene: NK7.1 / 41747
• FlyBaseID: FBgn0024321
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: XP_038962557.1
• Gene: Nkx2-4 / 366213
• RGDID: 1304985
• Length: 353
• Species: Rattus norvegicus
• Alignment Length: 357
• Identity: 92/357 - (25%)
• Similarity: 137/357 - (38%)
• Gaps: 77/357 - (21%)

  Fly   187 PPHPTPHSIADILGMSFVKKERPEVAFDAQGPAKSPNSILKPYQEQQPIRSSSISMSDASEEESA 251
            |.|.||.|::|||.......::.....|...|..........|: ..|...||.:.:.|..:...
  Rat     5 PKHTTPFSVSDILSPIEETYKKFGGVMDGAPPGLGAPLGAAAYR-APPTGPSSQAAAVAGMQPPH 68

  Fly   252 AVAGATSAATAAAAVAATITAATVATPLDQPLNLCVVKKSRDS-----------NNSPMPATKQS 305
            |:||..:||.||||.||...|||...|..       |.:...|           |...:||....
  Rat    69 AMAGHNAAAAAAAAAAAAAAAATYHMPPG-------VSQFPHSAMGSYCNGGLGNMGELPAYTDG 126

  Fly   306 QILGKSATKKESSGKPAAKKKKLSSTVALPPDISPTGSSDSLMRDKLMANNSSSPGSNVNAQMQS 370
            ...|.:|                ::|.....:..|..||.|    :.|     .|.:.||.....
  Rat   127 MRGGAAA----------------AATGWYGANTDPRYSSIS----RFM-----GPSAGVNVAGMG 166

  Fly   371 NANSTLETTEDDSDSGSTDARRKKKARTTFTGRQIFELEKMFENKKYLSASERTEMAKLLMVTET 435
            :.....:..:..:...:...|||:  |..|:..|::|||:.|:.:|||||.||..:|.::.:|.|
  Rat   167 SLTGIADAAKSLAPLHAAAPRRKR--RVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPT 229

  Fly   436 QVKIWFQNRRTKWKKQDNVTNNEAAEHKSSNAKPGATGTATTTPSGEPTDKR------------- 487
            ||||||||.|.|.|:|        |:.|::.......|.....|...|:.:|
  Rat   230 QVKIWFQNHRYKMKRQ--------AKDKAAQQLQQEGGLGPPPPPPPPSPRRVAVPVLVKDGKPC 286

  Fly   488 SSNATSPTVGN----------AATIAEIKKSP 509
            .:.|.:||.|.          |:.:.|:..||
  Rat   287 QNGAGTPTPGQGGQQPQAPTPASELEELSSSP 318

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NK7.1	NP_650357.2	Homeodomain	394..450	CDD:459649	27/55 (49%)
Nkx2-4	XP_038962557.1	Homeodomain	188..244	CDD:459649	29/57 (51%)