Protein Alignment NK7.1 and EVX2

DIOPT Version :10

• Sequence 1: NP_650357.2
• Gene: NK7.1 / 41747
• FlyBaseID: FBgn0024321
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_001073927.1
• Gene: EVX2 / 344191
• HGNCID: 3507
• Length: 476
• Species: Homo sapiens
• Alignment Length: 272
• Identity: 72/272 - (26%)
• Similarity: 104/272 - (38%)
• Gaps: 72/272 - (26%)

  Fly   180 AHVYDRLPPHPTPHSIADILGMSFVKKERPEVAFDAQGPAKSPNSILKPYQEQQPIRSSSISMSD 244
            |.:..|||..|...::.::                   |||....|...:..|.....|::|...
Human    47 ARLSPRLPSAPLHSALGEL-------------------PAKGKFEIDTLFNLQHTGSESTVSSEI 92

  Fly   245 ASEEESAAVAGATSAATAAAAVAATITAATVATPLDQPLNLCVVKKSRDSNNSPMPATKQSQILG 309
            :|..||....|..|.|.|.|.:::.:...            |...:|...             ||
Human    93 SSAAESRKKPGHYSEAAAEADMSSDVEVG------------CSALRSPGG-------------LG 132

  Fly   310 KSATKKESSGKPAAKKKKLSSTVALPPDISPTGSSDSLMRDKLMANNSSSPGSNVNAQMQSNANS 374
             :|..||::||..|:....:.|..     |.:||.       |.:.:..|.||..:|.:
Human   133 -AAQLKENNGKGYAESGSAAGTTT-----SASGSG-------LGSLHGGSGGSGGSAAL------ 178

  Fly   375 TLETTEDDSDSGSTDARRKKKARTTFTGRQIFELEKMFENKKYLSASERTEMAKLLMVTETQVKI 439
                  ..|.||:...||   .||.||..||..|||.|..:.|:|...|.|:|..|.:.||.:|:
Human   179 ------GGSGSGADQVRR---YRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKV 234

  Fly   440 WFQNRRTKWKKQ 451
            ||||||.|.|:|
Human   235 WFQNRRMKDKRQ 246

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NK7.1	NP_650357.2	Homeodomain	394..450	CDD:459649	26/55 (47%)
EVX2	NP_001073927.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	82..113		9/30 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	142..185		13/66 (20%)
		Homeodomain	189..245	CDD:459649	28/58 (48%)