Protein Alignment NK7.1 and HMX3

DIOPT Version :9

• Sequence 1: NP_001247103.1
• Gene: NK7.1 / 41747
• FlyBaseID: FBgn0024321
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_001099044.1
• Gene: HMX3 / 340784
• HGNCID: 5019
• Length: 357
• Species: Homo sapiens
• Alignment Length: 387
• Identity: 105/387 - (27%)
• Similarity: 146/387 - (37%)
• Gaps: 112/387 - (28%)

  Fly   172 PGPPTNWHAHVYDRLPPHPTPHSIADILGMSFVKKERPEVAFDAQGPAKSPNSILK--------- 227
            |||.....|....:.||.|.|                        .|.:||.||..
Human     4 PGPDAAGTASAQPQPPPPPPP------------------------APKESPFSIKNLLNGDHHRP 44

  Fly   228 PYQEQQPIRSSSISMSDASEEESAAVAGATSAATAAAAVAATITAATVATPLDQPLNLCVVKKSR 292
            |.:.|.|.|:..         ..|:.|.|.:||.||||..|...||..|  |.|..:|...:...
Human    45 PPKPQPPPRTLF---------APASAAAAAAAAAAAAAKGALEGAAGFA--LSQVGDLAFPRFEI 98

  Fly   293 DSNNSPMPA--TKQSQILGKSATKKESSG---KPAAKKKKLSSTVALPPDISPTGSSDSLMRDKL 352
            .:....:||  .::|.......|...:.|   :|.|.:|      ||..|.||...:|   ||
Human    99 PAQRFALPAHYLERSPAWWYPYTLTPAGGHLPRPEASEK------ALLRDSSPASGTD---RD-- 152

  Fly   353 MANNSSSPGSNVNA-----QMQSNANSTLETTEDDSDS-----------------------GSTD 389
                  ||...:.|     ::.|.:...:...|.||:.                       |:.|
Human   153 ------SPEPLLKADPDHKELDSKSPDEIILEESDSEESKKEGEAAPGAAGASVGAAAATPGAED 211

  Fly   390 ------------ARRKKKARTTFTGRQIFELEKMFENKKYLSASERTEMAKLLMVTETQVKIWFQ 442
                        |.||||.||.|:..|:|:||..|:.|:|||:|||..:|..|.:||||||||||
Human   212 WKKGAESPEKKPACRKKKTRTVFSRSQVFQLESTFDMKRYLSSSERAGLAASLHLTETQVKIWFQ 276

  Fly   443 NRRTKWKKQDNVTNNEAAEHKSSNAKPGATGTATTTPSGEPTDKRSSNATSPTVGNAATIAE 504
            |||.|||:|      .|||.:::|....|.......|.....:..:..|.:...|....:::
Human   277 NRRNKWKRQ------LAAELEAANLSHAAAQRIVRVPILYHENSAAEGAAAAAAGAPVPVSQ 332

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NK7.1	NP_001247103.1	Homeobox	397..449	CDD:278475	31/51 (61%)
HMX3	NP_001099044.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..58		17/86 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	129..229		23/116 (20%)
		Homeobox	230..283	CDD:278475	31/52 (60%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0485
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	3	2.770