DRSC/TRiP Functional Genomics Resources

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Protein Alignment NK7.1 and H2.0

DIOPT Version :10

Sequence 1:NP_650357.2 Gene:NK7.1 / 41747 FlyBaseID:FBgn0024321 Length:721 Species:Drosophila melanogaster
Sequence 2:NP_523488.2 Gene:H2.0 / 33841 FlyBaseID:FBgn0001170 Length:418 Species:Drosophila melanogaster


Alignment Length:477 Identity:102/477 - (21%)
Similarity:169/477 - (35%) Gaps:164/477 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly    84 PTSMTTHM-----VSPIGNSKEKLVNM---LRVRDNNNMASTISDSPPTTF------LQKQLEAV 134
            |.:::|||     |:|........||:   |..:::....:.:|.||.:..      |...::.:
  Fly    15 PENLSTHMYGECEVNPTLAKCPDPVNVDHELPTKESCASTTIVSTSPTSATSTTKVKLSFSVDRL 79

  Fly   135 VAPRPSSVHPQHQQPQQQTVQLQQQRRSVSTPA---------ITTTPGPPTNWHAHVYDR----- 185
            :...|...|                |:|.|:|:         :.....|.....|:...|     
  Fly    80 LGSEPEESH----------------RQSSSSPSTKSCCDGSILACCSFPHCFSQANAESRRFGHA 128

  Fly   186 -LPPHPTPHSIADILGMSFVKKERPEVAFDA--QGPAKSPNSILKPYQEQQPIRSSSISMSDASE 247
             |||..||.|          ....|.|..|.  .||.....|:|:|    .|||::         
  Fly   129 TLPPTFTPTS----------SHTYPFVGLDKLFPGPYMDYKSVLRP----TPIRAA--------- 170

  Fly   248 EESAAVAGATSAATAAAAVAA-----------------------------TITAATVATPLDQPL 283
             |.||....|.|..|......                             :.||:.:..||....
  Fly   171 -EHAAPTYPTLATNALLRFHQHQKQQHQQHHHHQHHPKHLHQQHKPPPHNSTTASALLAPLHSLT 234

  Fly   284 NLCVVKKSRDSNNSPMPATKQSQILGKSATKKESSGKPAAKKKKLSSTVALPPDISPTGSSDSLM 348
            :|.:.:             :|.:.|||:..:.                    .||:||       
  Fly   235 SLQLTQ-------------QQQRFLGKTPQQL--------------------LDIAPT------- 259

  Fly   349 RDKLMANNSSSPGSNVNAQMQSNA------NSTLETTEDDSDSGSTDARRKKKARTTFTGRQIFE 407
                      ||.:...|..|:.|      |.     :.::.:||...|::..:|..|:..|...
  Fly   260 ----------SPAAAAAATSQNGAHGHGGGNG-----QGNASAGSNGKRKRSWSRAVFSNLQRKG 309

  Fly   408 LEKMFENKKYLSASERTEMAKLLMVTETQVKIWFQNRRTKWKKQDNVTNNEAAEHKSSNAKPGAT 472
            ||..|:.:||::..:|.::|..|.:|:.|||:||||||.||:....  |.::.:.|..:|.|.:.
  Fly   310 LEIQFQQQKYITKPDRRKLAARLNLTDAQVKVWFQNRRMKWRHTRE--NLKSGQEKQPSAVPESG 372

  Fly   473 GT-ATTTPSGEPTDKRSSNATS 493
            |. .|:||||:.|.:.:.:.:|
  Fly   373 GVFKTSTPSGDGTPQEALDYSS 394

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
NK7.1NP_650357.2 Homeodomain 394..450 CDD:459649 23/55 (42%)
H2.0NP_523488.2 Homeodomain 292..352 CDD:459649 24/59 (41%)

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