Protein Alignment NK7.1 and HOXD13

DIOPT Version :10

• Sequence 1: NP_650357.2
• Gene: NK7.1 / 41747
• FlyBaseID: FBgn0024321
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_000514.2
• Gene: HOXD13 / 3239
• HGNCID: 5136
• Length: 343
• Species: Homo sapiens
• Alignment Length: 311
• Identity: 70/311 - (22%)
• Similarity: 103/311 - (33%)
• Gaps: 94/311 - (30%)

  Fly   234 PIRSSSISMSDASEEE------SAAVAGATSAATAAAAVAATITAATVATPLDQPLNLCVVKKSR 292
            |..|||.|::.|:...      ||.|...|.:..||||.||...||..|:....|........|.
Human    23 PASSSSSSVAAAAASGQCRGFLSAPVFAGTHSGRAAAAAAAAAAAAAAASGFAYPGTSERTGSSS 87

  Fly   293 DSNNSPMPATKQSQILGKSATKKESSGKPAAKKK-----------------KLSSTVALPPDI-- 338
            .|::|.:.|.:......|.......:...||...                 ::|..|.|..:.
Human    88 SSSSSAVVAARPEAPPAKECPAPTPAAAAAAPPSAPALGYGYHFGNGYYSCRMSHGVGLQQNALK 152

  Fly   339 -SPTGSSDSLMRDKLM----ANNSSSPGSNVNAQ------------------------------- 367
             ||..|......:|.|    ..:||.|.:.|.|:
Human   153 SSPHASLGGFPVEKYMDVSGLASSSVPANEVPARAKEVSFYQGYTSPYQHVPGYIDMVSTFGSGE 217

  Fly   368 ----------------MQSNANSTLETTED--------------DSDSGSTDA---RRKKKARTT 399
                            :.:..||.:..|:|              |......|.   ||.:|.|..
Human   218 PRHEAYISMEGYQSWTLANGWNSQVYCTKDQPQGSHFWKSSFPGDVALNQPDMCVYRRGRKKRVP 282

  Fly   400 FTGRQIFELEKMFENKKYLSASERTEMAKLLMVTETQVKIWFQNRRTKWKK 450
            :|..|:.|||..:...|:::..:|..::....::|.||.|||||||.|.||
Human   283 YTKLQLKELENEYAINKFINKDKRRRISAATNLSERQVTIWFQNRRVKDKK 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NK7.1	NP_650357.2	Homeodomain	394..450	CDD:459649	20/55 (36%)
HOXD13	NP_000514.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..28		2/4 (50%)
		polyalanine repeat	57..71		8/13 (62%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	78..115		5/36 (14%)
		HoxA13_N	<100..172	CDD:463521	11/71 (15%)
		Homeodomain	277..333	CDD:459649	20/55 (36%)