Protein Alignment NK7.1 and HOXD11

DIOPT Version :10

• Sequence 1: NP_650357.2
• Gene: NK7.1 / 41747
• FlyBaseID: FBgn0024321
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_067015.2
• Gene: HOXD11 / 3237
• HGNCID: 5134
• Length: 338
• Species: Homo sapiens
• Alignment Length: 327
• Identity: 76/327 - (23%)
• Similarity: 111/327 - (33%)
• Gaps: 88/327 - (26%)

  Fly   186 LPPHPTPHSIADILGMSFVKKERPEVAFDAQGPAKSPNSILKPYQEQQPIRSSSISMSDASEEES 250
            |.||..|           |:    ||||...|..::.    .||:......|:....|.......
Human    51 LAPHVQP-----------VR----EVAFRDYGLERAK----WPYRGGGGGGSAGGGSSGGGPGGG 96

  Fly   251 AAVAGATSAATAAAAVAATITAATVATPLDQPLNLCVVKKSRDSNNSPMPATKQSQILGKS---- 311
            ...||..:...||||.||...||.....:.:.|             .| ||.::..:|.|:
Human    97 GGGAGGYAPYYAAAAAAAAAAAAAEEAAMQREL-------------LP-PAGRRPDVLFKAPEPV 147

  Fly   312 -ATKKESSGKPAAKKKKLSSTVA------------------------------LPPDISPTGSSD 345
             |......| ||.......|.|.                              .||  .|.|::|
Human   148 CAAPGPPHG-PAGAASNFYSAVGRNGILPQGFDQFYEAAPGPPFAGPQPPPPPAPP--QPEGAAD 209

  Fly   346 SLMRDKLMANNSSSPGSNVNAQMQSNANSTLETTEDDSD-----------SGSTDARRKKKARTT 399
            .  .|...............|...|......|.:..|.:           |.:...:|.:|.|..
Human   210 K--GDPRTGAGGGGGSPCTKATPGSEPKGAAEGSGGDGEGPPGEAGAEKSSSAVAPQRSRKKRCP 272

  Fly   400 FTGRQIFELEKMFENKKYLSASERTEMAKLLMVTETQVKIWFQNRRTKWKKQDNVTNNEAAEHKS 464
            :|..||.|||:.|....|::..:|.:::::|.:|:.||||||||||.|.||    .|.:..::.:
Human   273 YTKYQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKK----LNRDRLQYFT 333

  Fly   465 SN 466
            .|
Human   334 GN 335

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NK7.1	NP_650357.2	Homeodomain	394..450	CDD:459649	24/55 (44%)
HOXD11	NP_067015.2	DUF3528	26..185	CDD:432284	36/167 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	179..270		13/94 (14%)
		Homeodomain	267..323	CDD:459649	24/55 (44%)