Protein Alignment NK7.1 and HOXC11

DIOPT Version :10

• Sequence 1: NP_650357.2
• Gene: NK7.1 / 41747
• FlyBaseID: FBgn0024321
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_055027.1
• Gene: HOXC11 / 3227
• HGNCID: 5123
• Length: 304
• Species: Homo sapiens
• Alignment Length: 276
• Identity: 64/276 - (23%)
• Similarity: 108/276 - (39%)
• Gaps: 72/276 - (26%)

  Fly   212 AFDAQGPAKSPNSILKPYQEQ-QPIRSSSISMSDASE-----EESAAVAGATSAATAAAAVAATI 270
            :|..|.|::   .|..||..| .|:|..|..:..:.:     ..|:..|.|...........:|:
Human    49 SFLPQAPSR---QISYPYSAQVPPVREVSYGLEPSGKWHHRNSYSSCYAAADELMHRECLPPSTV 110

  Fly   271 T----------------AATVATPLDQPLNLCVVKKSRDSNNSPMPATKQSQIL----------- 308
            |                :|..|||..        ..|..:.||.:|     |..
Human   111 TEILMKNEGSYGGHHHPSAPHATPAG--------FYSSVNKNSVLP-----QAFDRFFDNAYCGG 162

  Fly   309 GKSATKKESSGKPAAKKKKLSSTVALPPDISPTGSSDSLMRDKLMANNSSSPGSNVNAQMQ---- 369
            |....:...|||..||.:         |:..|...         :|:.:.: |:...|:.:
Human   163 GDPPAEPPCSGKGEAKGE---------PEAPPASG---------LASRAEA-GAEAEAEEENTNP 208

  Fly   370 SNANSTLETTEDDSDSGSTDARRKKKARTTFTGRQIFELEKMFENKKYLSASERTEMAKLLMVTE 434
            |::.|.....::.:...:.:|.|.:|.|..::..||.|||:.|....|::..:|.:::::|.:|:
Human   209 SSSGSAHSVAKEPAKGAAPNAPRTRKKRCPYSKFQIRELEREFFFNVYINKEKRLQLSRMLNLTD 273

  Fly   435 TQVKIWFQNRRTKWKK 450
            .||||||||||.|.||
Human   274 RQVKIWFQNRRMKEKK 289

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NK7.1	NP_650357.2	Homeodomain	394..450	CDD:459649	23/55 (42%)
HOXC11	NP_055027.1	DUF3528	42..161	CDD:432284	24/127 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	166..237		15/89 (17%)
		Homeodomain	233..289	CDD:459649	23/55 (42%)