Protein Alignment NK7.1 and HOXC4

DIOPT Version :10

• Sequence 1: NP_650357.2
• Gene: NK7.1 / 41747
• FlyBaseID: FBgn0024321
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_055435.2
• Gene: HOXC4 / 3221
• HGNCID: 5126
• Length: 264
• Species: Homo sapiens
• Alignment Length: 327
• Identity: 75/327 - (22%)
• Similarity: 108/327 - (33%)
• Gaps: 111/327 - (33%)

  Fly   179 HAHVYDRLPPHPTPHSIADILGMSFVKKERPEVAFDAQGPAKSPNSILKPYQEQQPIRSSSISMS 243
            |..:|...||.|:             ..||.......|||..|............|.:|.|:.
Human    49 HQELYPPPPPRPS-------------YPERQYSCTSLQGPGNSRGHGPAQAGHHHPEKSQSLC-- 98

  Fly   244 DASEEESAAVAGATSAATAAAAVAATITAATVATPLDQPLNLCVVKKSRDSNNSPMPATKQSQIL 308
                 |.|.::||:::.:.|.      .|.:...| |.|
Human    99 -----EPAPLSGASASPSPAP------PACSQPAP-DHP-------------------------- 125

  Fly   309 GKSATKKESSGKPAAKKKKLSSTVALPPDISPTGSSDSLMRDKLMANNSSSPGSNVNAQMQSNAN 373
             .||..|:....|..||..:|:       ::|.             .|...|
Human   126 -SSAASKQPIVYPWMKKIHVST-------VNPN-------------YNGGEP------------- 156

  Fly   374 STLETTEDDSDSGSTDARRKKKARTTFTGRQIFELEKMFENKKYLSASERTEMAKLLMVTETQVK 438
                                |::||.:|.:|:.||||.|...:||:...|.|:|..|.::|.|:|
Human   157 --------------------KRSRTAYTRQQVLELEKEFHYNRYLTRRRRIEIAHSLCLSERQIK 201

  Fly   439 IWFQNRRTKWKKQDNVTNNEAAEHKSSNAKPGATGTATTTPSGEPTDKRSSNATSPTVGNAATIA 503
            |||||||.||||...:.|.:......:.|.|.....||...|    :..|.:||.|....|..|.
Human   202 IWFQNRRMKWKKDHRLPNTKVRSAPPAGAAPSTLSAATPGTS----EDHSQSATPPEQQRAEDIT 262

  Fly   504 EI 505
            .:
Human   263 RL 264

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NK7.1	NP_650357.2	Homeodomain	394..450	CDD:459649	28/55 (51%)
HOXC4	NP_055435.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	19..130		25/134 (19%)
		Antp-type hexapeptide	135..140		1/4 (25%)
		Homeodomain	157..213	CDD:459649	28/55 (51%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	214..264		12/53 (23%)