Protein Alignment NK7.1 and HOXB5

DIOPT Version :10

• Sequence 1: NP_650357.2
• Gene: NK7.1 / 41747
• FlyBaseID: FBgn0024321
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_002138.1
• Gene: HOXB5 / 3215
• HGNCID: 5116
• Length: 269
• Species: Homo sapiens
• Alignment Length: 238
• Identity: 72/238 - (30%)
• Similarity: 98/238 - (41%)
• Gaps: 47/238 - (19%)

  Fly   239 SISMSDASEEESAAVAGATSAATAAAAVAATITAATVATPLDQPLNLCVVKKSRDSNNSPMPATK 303
            |::.|.||.....|| |.:|.|..|.|.......|..:..|..|.:|              |.|.
Human    55 SVNRSSASSSHFGAV-GESSRAFPAPAQEPRFRQAASSCSLSSPESL--------------PCTN 104

  Fly   304 QSQILGKSATKKESSGKPAAKKKKLSSTVALPPDISPTGSSDSLMRDKLMANNSSSPGSNVNAQM 368
                 |.|...|.|:..|:.:....||:.........:.||:    .:..|:..||| |...||.
Human   105 -----GDSHGAKPSASSPSDQATSASSSANFTEIDEASASSE----PEEAASQLSSP-SLARAQP 159

  Fly   369 QSNANSTLETTEDDSDSGSTDA----RRK------------KKARTTFTGRQIFELEKMFENKKY 417
            :..|.||.      :..|.|..    .||            |:|||.:|..|..||||.|...:|
Human   160 EPMATSTA------APEGQTPQIFPWMRKLHISHDMTGPDGKRARTAYTRYQTLELEKEFHFNRY 218

  Fly   418 LSASERTEMAKLLMVTETQVKIWFQNRRTKWKKQDNVTNNEAA 460
            |:...|.|:|..|.::|.|:||||||||.||||.:.:.:...|
Human   219 LTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNKLKSMSLA 261

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NK7.1	NP_650357.2	Homeodomain	394..450	CDD:459649	29/55 (53%)
HOXB5	NP_002138.1	PRK07003	<67..>171	CDD:235906	32/134 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	77..173		28/125 (22%)
		Antp-type hexapeptide	176..181		0/4 (0%)
		Homeodomain	195..251	CDD:459649	29/55 (53%)