Protein Alignment NK7.1 and HOXA13

DIOPT Version :10

• Sequence 1: NP_650357.2
• Gene: NK7.1 / 41747
• FlyBaseID: FBgn0024321
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_000513.2
• Gene: HOXA13 / 3209
• HGNCID: 5102
• Length: 388
• Species: Homo sapiens
• Alignment Length: 336
• Identity: 78/336 - (23%)
• Similarity: 118/336 - (35%)
• Gaps: 86/336 - (25%)

  Fly   192 PHSIADILGMSFVKKERPEVAFDAQGPAKSPNSILKPYQEQQPIRSSSISMSDASEEESAAVAGA 256
            ||..|...|.:|  ......|..|...|....:::.......|..:|:.|.:......|||.|.|
Human    59 PHPAAAAAGGNF--SVAAAAAAAAAAAANQCRNLMAHPAPLAPGAASAYSSAPGEAPPSAAAAAA 121

  Fly   257 TSAATAAAAVAATIT------------AATVATPLDQPLNLCVVKKSRDSNNSPMP--------- 300
            .:||.||||.||:.:            ||...:|       |.......|..:.:|
Human   122 AAAAAAAAAAAASSSGGPGPAGPAGAEAAKQCSP-------CSAAAQSSSGPAALPYGYFGSGYY 179

  Fly   301 ---------------------------ATKQSQILGKSATKKESSGK------------PAAKKK 326
                                       |.|.....|.:|.:..|..|            |....:
Human   180 PCARMGPHPNAIKSCAQPASAAAAAAFADKYMDTAGPAAEEFSSRAKEFAFYHQGYAAGPYHHHQ 244

  Fly   327 KLSSTVALP--PDISPTGSSDSLMRDKL-MANNSSSP---GSNVNAQM-----QSNANSTLETTE 380
            .:...:.:|  |.:...|.|   ..:.| :...|..|   .:..|.||     |:......::|.
Human   245 PMPGYLDMPVVPGLGGPGES---RHEPLGLPMESYQPWALPNGWNGQMYCPKEQAQPPHLWKSTL 306

  Fly   381 DDSDSGSTDA---RRKKKARTTFTGRQIFELEKMFENKKYLSASERTEMAKLLMVTETQVKIWFQ 442
            .|..|..:||   ||.:|.|..:|..|:.|||:.:...|:::..:|..::....::|.||.||||
Human   307 PDVVSHPSDASSYRRGRKKRVPYTKVQLKELEREYATNKFITKDKRRRISATTNLSERQVTIWFQ 371

  Fly   443 NRRTKWKKQDN 453
            |||.|.||..|
Human   372 NRRVKEKKVIN 382

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NK7.1	NP_650357.2	Homeodomain	394..450	CDD:459649	20/55 (36%)
HOXA13	NP_000513.2	HoxA13_N	85..224	CDD:463521	26/145 (18%)
		Homeodomain	323..379	CDD:459649	20/55 (36%)