Protein Alignment NK7.1 and HMX1

DIOPT Version :10

• Sequence 1: NP_650357.2
• Gene: NK7.1 / 41747
• FlyBaseID: FBgn0024321
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_061815.2
• Gene: HMX1 / 3166
• HGNCID: 5017
• Length: 348
• Species: Homo sapiens
• Alignment Length: 198
• Identity: 61/198 - (30%)
• Similarity: 86/198 - (43%)
• Gaps: 22/198 - (11%)

  Fly   334 LPPDISPTGS---SDSLMRDKLMANNSSSPGSNVNAQMQSNANSTLETTEDDSDSGSTDAR---- 391
            |.||.|...|   .:.:.|.:........||:......:..|......||:.|:.....|.
Human   128 LSPDTSDRDSPETGEEMGRAEGAWPRGPGPGAVQREAAELAARGPAAGTEEASELAEVPAAAGET 192

  Fly   392 ---------RKKKARTTFTGRQIFELEKMFENKKYLSASERTEMAKLLMVTETQVKIWFQNRRTK 447
                     ||||.||.|:..|:|:||..|:.|:|||::||..:|..|.:|||||||||||||.|
Human   193 RGGVGVGGGRKKKTRTVFSRSQVFQLESTFDLKRYLSSAERAGLAASLQLTETQVKIWFQNRRNK 257

  Fly   448 WKKQDNVTNNEAAEHKSSNAKPGATGTATTTPSGEPTDKRSSNATSPTVGNAATIAEIKKSPKSP 512
            ||:|      .|||.::::..|.........|........::.|..|.......:|....:|..|
Human   258 WKRQ------LAAELEAASLSPPGAQRLVRVPVLYHESPPAAAAAGPPATLPFPLAPAAPAPPPP 316

  Fly   513 NRG 515
            ..|
Human   317 LLG 319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NK7.1	NP_650357.2	Homeodomain	394..450	CDD:459649	33/55 (60%)
HMX1	NP_061815.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	29..203		13/74 (18%)
		Homeodomain	206..260	CDD:459649	31/53 (58%)
		HMX family specific domain 1	263..273		3/9 (33%)
		HMX family specific domain 2	276..289		1/12 (8%)