Protein Alignment NK7.1 and en1a

DIOPT Version :10

• Sequence 1: NP_650357.2
• Gene: NK7.1 / 41747
• FlyBaseID: FBgn0024321
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_571120.2
• Gene: en1a / 30244
• ZFINID: ZDB-GENE-980526-216
• Length: 231
• Species: Danio rerio
• Alignment Length: 309
• Identity: 74/309 - (23%)
• Similarity: 113/309 - (36%)
• Gaps: 105/309 - (33%)

  Fly   172 PGPPTNWHAHVYDRLPPH-PTPHSIADILGMSF-VKKERPEVAFDAQGPAKSPNSILKPYQEQQP 234
            |.||.         ||.| .|...|.:||...| .|:||..|..|:   ...|.::|.
Zfish    19 PSPPL---------LPAHRNTDFFIDNILRPDFGCKRERERVTRDS---GVRPTAVLD------- 64

  Fly   235 IRSSSISMSDASEEESAAVAGATSAATAAAAVAATITAATVATPLDQPLNLCVVKKSRDSNNSPM 299
                  |.||          |.:|:|           ::||::|:
Zfish    65 ------SRSD----------GVSSSA-----------SSTVSSPV-------------------- 82

  Fly   300 PATKQSQILGKSATKKESSGKPAAKKKKLSSTVALPPDISPTGSSDSLMRDKLMANNSSSPGSNV 364
             ::.||..:.:.::|..|..|.:.|:      :..|..:..|..||           ..|.|...
Zfish    83 -SSSQSNKVEQGSSKSSSPSKDSQKQ------ILWPAWVYCTRYSD-----------RPSSGPRT 129

  Fly   365 NAQMQSNANSTLETTEDDSDSGSTDARRKKKARTTFTGRQIFELEKMFENKKYLSASERTEMAKL 429
            ....:.|.|     ||.|.          |:.||.||..|:..|:..|:..:|::...|..:|:.
Zfish   130 RKLKKKNNN-----TESDD----------KRPRTAFTAEQLQRLKAEFQTSRYITEQRRQALARE 179

  Fly   430 LMVTETQVKIWFQNRRTKWKKQDNVTNNEAAEHKSSNAKPGATGTATTT 478
            |.:.|:|:||||||:|.|.||.....|..|.:..:.    |....:|||
Zfish   180 LGLNESQIKIWFQNKRAKIKKSSGFKNALAMQLMAQ----GLYNHSTTT 224

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NK7.1	NP_650357.2	Homeodomain	394..450	CDD:459649	22/55 (40%)
en1a	NP_571120.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..29		6/18 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	43..105		21/119 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	121..148		9/52 (17%)
		Homeodomain	144..200	CDD:459649	22/55 (40%)
		Engrail_1_C_sig	201..230	CDD:431338	6/28 (21%)