Protein Alignment NK7.1 and GBX2

DIOPT Version :9

• Sequence 1: NP_001247103.1
• Gene: NK7.1 / 41747
• FlyBaseID: FBgn0024321
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_001476.2
• Gene: GBX2 / 2637
• HGNCID: 4186
• Length: 348
• Species: Homo sapiens
• Alignment Length: 370
• Identity: 94/370 - (25%)
• Similarity: 130/370 - (35%)
• Gaps: 117/370 - (31%)

  Fly   122 PPTTFLQKQLEAVVAPRPSSVHPQHQQPQQQT--VQLQQQRRSVSTPAITTTPG----PPTNWHA 180
            ||....|..|:..:.|    .||.||.|...|  .....|..::::..:.|.||    .|.:..|
Human    61 PPPALPQAALQPALPP----AHPHHQIPSLPTGFCSSLAQGMALTSTLMATLPGGFSASPQHQEA 121

  Fly   181 HVYDRLPPHPTPHSIADILGMSFVKKERPEV-AFDAQGPAKSPNSILKPYQEQQPIRSSSISMSD 244
            ....:..|.|.|.      |.:|.|.|..:. |.|.:|......|:|
Human   122 AAARKFAPQPLPG------GGNFDKAEALQADAEDGKGFLAKEGSLL------------------ 162

  Fly   245 ASEEESAAVAGATSAATAAAAVAATITAATVATPLDQPLNLCVVKKSRDSNNSPMPATKQSQILG 309
                              |.:.|.|:.|:.|.....|                           |
Human   163 ------------------AFSAAETVQASLVGAVRGQ---------------------------G 182

  Fly   310 KSATKKESSGKPAAKKKKLSSTVALPPDISPTGSSDSLMRDKLMANNSSSPGSNVNAQMQSNANS 374
            |..:|.|...|...:...|.|.|....|.:.||.:         |:....||           ::
Human   183 KDESKVEDDPKGKEESFSLESDVDYSSDDNLTGQA---------AHKEEDPG-----------HA 227

  Fly   375 TLETTEDDSDSGSTDARRK-KKARTTFTGRQIFELEKMFENKKYLSASERTEMAKLLMVTETQVK 438
            ..||......:|||.:..| ::.||.||..|:.||||.|..|||||.:||:::|..|.::|.|||
Human   228 LEETPPSSGAAGSTTSTGKNRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVK 292

  Fly   439 IWFQNRRTKWKKQDNVTNNEAAEHKSSNAKPGATGTATTTPSGEP 483
            |||||||.|||:                .|.|...:.|..||..|
Human   293 IWFQNRRAKWKR----------------VKAGNANSKTGEPSRNP 321

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NK7.1	NP_001247103.1	Homeobox	397..449	CDD:278475	31/51 (61%)
GBX2	NP_001476.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	59..81		7/23 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	111..139		6/33 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	179..251		21/118 (18%)
		Homeobox	250..303	CDD:306543	31/52 (60%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910