Protein Alignment NK7.1 and GSX1

DIOPT Version :10

• Sequence 1: NP_650357.2
• Gene: NK7.1 / 41747
• FlyBaseID: FBgn0024321
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_663632.1
• Gene: GSX1 / 219409
• HGNCID: 20374
• Length: 264
• Species: Homo sapiens
• Alignment Length: 344
• Identity: 88/344 - (25%)
• Similarity: 118/344 - (34%)
• Gaps: 111/344 - (32%)

  Fly   202 SFVKKERPEVAFDAQGPAKSPNSILKPYQEQQPIRSSSISMSDASEEESAAVAGATSAATAAAAV 266
            |.|.:|    |.:.:.|..||..:. ||....|.....:|            .||..|..|..
Human     9 SLVLRE----AGEKKAPEGSPPPLF-PYAVPPPHALHGLS------------PGACHARKAGL-- 54

  Fly   267 AATITAATVATPLDQPLNLCVVKKSRDSNNSPMPATKQSQILGKSATKKESSGKPAAKKKKLSST 331
                              |||         .|:..| .||:.|       ..|.||....|.|
Human    55 ------------------LCV---------CPLCVT-ASQLHG-------PPGPPALPLLKAS-- 82

  Fly   332 VALPPDIS-----PTGSSDSLMRDKLMANNSSSPGSNVNAQMQSNANSTLETTED---------- 381
              .||..|     |.|...|.:          |||........:.|.:..:|:..
Human    83 --FPPFGSQYCHAPLGRQHSAV----------SPGVAHGPAAAAAAAALYQTSYPLPDPRQFHCI 135

  Fly   382 DSDSGSTDARRKKKARTTFTGRQIFELEKMFENKKYLSASERTEMAKLLMVTETQVKIWFQNRRT 446
            ..||.|......|:.||.||..|:.|||:.|.:..|||...|.|:|..|.::|.||||||||||.
Human   136 SVDSSSNQLPSSKRMRTAFTSTQLLELEREFASNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRV 200

  Fly   447 KWKKQDNVTNNEAAEHKSSNAKPGATGTATTTPSGEPTDKRSSNATSPTVGNAATIAEIKKS--- 508
            |.||          |.|.||.:.|..|.|            ....::|.....|:::..|.|
Human   201 KHKK----------EGKGSNHRGGGGGGA------------GGGGSAPQGCKCASLSSAKCSEDD 243

  Fly   509 ---PKSPNRGSNNNNNNTL 524
               |.||:....::.:.|:
Human   244 DELPMSPSSSGKDDRDLTV 262

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NK7.1	NP_650357.2	Homeodomain	394..450	CDD:459649	29/55 (53%)
GSX1	NP_663632.1	SNAG domain. /evidence=ECO:0000250	1..20		4/14 (29%)
		Homeodomain	148..204	CDD:459649	29/55 (53%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	201..264		18/84 (21%)