Protein Alignment NK7.1 and Tlx2

DIOPT Version :10

• Sequence 1: NP_650357.2
• Gene: NK7.1 / 41747
• FlyBaseID: FBgn0024321
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_033418.1
• Gene: Tlx2 / 21909
• MGIID: 1350935
• Length: 284
• Species: Mus musculus
• Alignment Length: 297
• Identity: 77/297 - (25%)
• Similarity: 107/297 - (36%)
• Gaps: 89/297 - (29%)

  Fly   180 AHVYDRLPPH-PTPHSIADILGMSFVKKERPEVAFDAQGPAKSPNSILKPYQEQQPIRSSSISMS 243
            ||   .||.| |....|..||                .|| :.|...|.|.|..|....|:...|
Mouse     8 AH---HLPHHEPISFGIDQIL----------------SGP-EPPGGGLGPGQSGQSHGESAAFSS 52

  Fly   244 DASEEESAAVAGATSAATAAAAVAATITAATVATPLDQPLNLCVVKKSRDSNNSPMPATKQSQIL 308
            ........|.||:.::....:.|.   ....:..|..:||              |:|
Mouse    53 GFHGASGYAPAGSLASLPRGSGVG---PGGVIRVPAHRPL--------------PVP-------- 92

  Fly   309 GKSATKKESSGKPAAKKKKLSSTVALPPDISPTG-----------SSDSLMRDKLMANNSSSPGS 362
                  ..|...||         |..|..:...|           |.....:|:|.|  :.||.|
Mouse    93 ------PPSGAAPA---------VPGPSGLGGAGGLAGLTFPWMDSGRRFAKDRLTA--ALSPFS 140

  Fly   363 NVNAQMQSNANSTLETTEDDSDSGSTDARRKKKARTTFTGRQIFELEKMFENKKYLSASERTEMA 427
            ..........|.|              ..::||.||:|:..|:.|||:.|..:|||:::||..:|
Mouse   141 GTRRIGHPYQNRT--------------PPKRKKPRTSFSRSQVLELERRFLRQKYLASAERAALA 191

  Fly   428 KLLMVTETQVKIWFQNRRTKWKKQDNVTNNEAAEHKS 464
            |.|.:|:.|||.|||||||||::| .....||..|::
Mouse   192 KALRMTDAQVKTWFQNRRTKWRRQ-TAEEREAERHRA 227

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NK7.1	NP_650357.2	Homeodomain	394..450	CDD:459649	31/55 (56%)
Tlx2	NP_033418.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	20..52		11/48 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	78..104		9/62 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	140..166		8/39 (21%)
		Homeodomain	158..214	CDD:459649	31/55 (56%)