Protein Alignment NK7.1 and EMX1

DIOPT Version :10

• Sequence 1: NP_650357.2
• Gene: NK7.1 / 41747
• FlyBaseID: FBgn0024321
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_004088.2
• Gene: EMX1 / 2016
• HGNCID: 3340
• Length: 290
• Species: Homo sapiens
• Alignment Length: 279
• Identity: 67/279 - (24%)
• Similarity: 112/279 - (40%)
• Gaps: 53/279 - (18%)

  Fly   217 GPAKSPNSILKPYQEQQPIRSSSISMSDASEEESAAVAGATSAATAAAAVAATITAATVATPLDQ 281
            |...:.:.:|.....::|:|.::::....|..|:|.|:|..:|| ||.|..:......:..|
Human    60 GGGGAGSHLLAAAASEEPLRPTALNYPHPSAAEAAFVSGFPAAA-AAGAGRSLYGGPELVFP--- 120

  Fly   282 PLNLCVVKKSRDSNNSPMPATKQSQILGKSATKKESSGKPAAKKKKLSSTVALPPDISPTGSSDS 346
                       ::.|.|......:..||.|..:...|...|..:.        |....|....:.
Human   121 -----------EAMNHPALTVHPAHQLGASPLQPPHSFFGAQHRD--------PLHFYPWVLRNR 166

  Fly   347 LMRDKLMANNSSSPGSNVNAQMQSNANSTLETTEDDSDSGSTDARRKKKARTTFTGRQIFELEKM 411
            ....:..|::....|..::...                     ||:.|:.||.|:..|:..||:.
Human   167 FFGHRFQASDVPQDGLLLHGPF---------------------ARKPKRIRTAFSPSQLLRLERA 210

  Fly   412 FENKKYLSASERTEMAKLLMVTETQVKIWFQNRRTKWKKQDNVTNNEAAEHKSSNAKPGA----- 471
            ||...|:..:||.::|..|.::|||||:||||||||:|:|........:|.|    |.|:
Human   211 FEKNHYVVGAERKQLAGSLSLSETQVKVWFQNRRTKYKRQKLEEEGPESEQK----KKGSHHINR 271

  Fly   472 TGTATTTPSGEPTDKRSSN 490
            ...||...:||..|..|::
Human   272 WRIATKQANGEDIDVTSND 290

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NK7.1	NP_650357.2	Homeodomain	394..450	CDD:459649	27/55 (49%)
EMX1	NP_004088.2	Homeodomain	193..249	CDD:459649	27/55 (49%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	249..290		11/44 (25%)