Protein Alignment NK7.1 and Pdx1

DIOPT Version :10

• Sequence 1: NP_650357.2
• Gene: NK7.1 / 41747
• FlyBaseID: FBgn0024321
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_032840.1
• Gene: Pdx1 / 18609
• MGIID: 102851
• Length: 284
• Species: Mus musculus
• Alignment Length: 234
• Identity: 63/234 - (26%)
• Similarity: 93/234 - (39%)
• Gaps: 68/234 - (29%)

  Fly   335 PPDIS-----PTGSSD---SLMRDKLMAN------------NSSSPGSNVNAQMQSNANSTLETT 379
            |||||     |..|.|   :.:...|.|.            |.:.||..............:::|
Mouse    62 PPDISPYEVPPLASDDPAGAHLHHHLPAQLGLAHPPPGPFPNGTEPGGLEEPNRVQLPFPWMKST 126

  Fly   380 EDDSDSG-------STDARRKKKARTTFTGRQIFELEKMFENKKYLSASERTEMAKLLMVTETQV 437
            :..:..|       :.:....|:.||.:|..|:.||||.|...||:|...|.|:|.:|.:||..:
Mouse   127 KAHAWKGQWAGGAYTAEPEENKRTRTAYTRAQLLELEKEFLFNKYISRPRRVELAVMLNLTERHI 191

  Fly   438 KIWFQNRRTKWKKQDNVTNNEAAEHKSSNAKPGATG-------TATTT----------------- 478
            ||||||||.||||:::       :.:||....|..|       .|.|:
Mouse   192 KIWFQNRRMKWKKEED-------KKRSSGTPSGGGGGEEPEQDCAVTSGEELLAVPPLPPPGGAV 249

  Fly   479 PSGEPTDKR-----SSNATSPTVGNAATIAEIKKSPKSP 512
            |.|.|...|     |..:.||   ..::||.::  |:.|
Mouse   250 PPGVPAAVREGLLPSGLSVSP---QPSSIAPLR--PQEP 283

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NK7.1	NP_650357.2	Homeodomain	394..450	CDD:459649	29/55 (53%)
Pdx1	NP_032840.1	Transactivation domain. /evidence=ECO:0000250	13..73		5/10 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	30..116		13/53 (25%)
		Antp-type hexapeptide	119..124		0/4 (0%)
		Homeodomain	148..204	CDD:459649	29/55 (53%)
		Nuclear localization signal	198..204		4/5 (80%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	202..284		20/94 (21%)