DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NK7.1 and Nkx3-1

DIOPT Version :9

Sequence 1:	NP_001247103.1	Gene:	NK7.1 / 41747	FlyBaseID:	FBgn0024321	Length:	721	Species:	Drosophila melanogaster
Sequence 2:	NP_035051.1	Gene:	Nkx3-1 / 18095	MGIID:	97352	Length:	237	Species:	Mus musculus

Alignment Length:	176	Identity:	53/176 - (30%)
Similarity:	76/176 - (43%)	Gaps:	45/176 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   316 ESSGK-----PAAKKKKLSSTVALP---------------PDISPTGSSDSLMRDKLMANNSSSP 360
            |:.|:     |..:.|:|:|.:...               |..||....||............:|
Mouse    13 EAGGRSPWAAPPTQSKRLTSFLIQDILRDRAERHGGHSGNPQHSPDPRRDSAPEPDKAGGRGVAP 77

  Fly   361 GSNVNAQMQSNANSTLET-TEDDSD-------------------SGSTDARRKKKARTTFTGRQI 405
                 ....|..:|..|| ||.:||                   :.....:.:|::|..|:..|:
Mouse    78 -----EDPPSIRHSPAETPTEPESDAHFETYLLDCEHNPGDLASAPQVTKQPQKRSRAAFSHTQV 137

  Fly   406 FELEKMFENKKYLSASERTEMAKLLMVTETQVKIWFQNRRTKWKKQ 451
            .|||:.|.::|||||.||..:||.|.:|||||||||||||.|.|::
Mouse   138 IELERKFSHQKYLSAPERAHLAKNLKLTETQVKIWFQNRRYKTKRK 183

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NK7.1	NP_001247103.1	Homeobox	397..449	CDD:278475	31/51 (61%)
Nkx3-1	NP_035051.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..96		18/87 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	108..130		1/21 (5%)
		Homeobox	128..181	CDD:278475	31/52 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167833358
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840