Protein Alignment NK7.1 and Nkx2-6

DIOPT Version :10

• Sequence 1: NP_650357.2
• Gene: NK7.1 / 41747
• FlyBaseID: FBgn0024321
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_035050.2
• Gene: Nkx2-6 / 18092
• MGIID: 97351
• Length: 289
• Species: Mus musculus
• Alignment Length: 372
• Identity: 82/372 - (22%)
• Similarity: 127/372 - (34%)
• Gaps: 140/372 - (37%)

  Fly   187 PPHPTPHSIADILGMSFVKKERPEVAFDAQGPAKSPNSILKPYQ-EQQPIRSSSISMSDASEEES 250
            |...||.|:||||.:...:|:               :..|..:: .:.|::...:.|:..|
Mouse     5 PVASTPFSVADILRLECQQKD---------------SKTLSQWELHRNPVKPRYLRMNQES---- 50

  Fly   251 AAVAGATSAATAAAAVAATITAATVATPLDQPLNLCVVKKSRDSNNSPMPATKQSQILGKSATKK 315
                |...::..|.||....|..||.                :..::|:
Mouse    51 ----GWFESSDRAQAVPFRCTWETVL----------------EMGSNPV---------------- 79

  Fly   316 ESSGKPAAKKKKLSSTVALPPDISPTGSSDSLMRDKLMANNSSSPGSNVNAQMQSNANSTLETTE 380
               |:|...          |..||..|:.:. |.|:.:.|.|.
Mouse    80 ---GEPQTP----------PGTISRLGARNP-MTDRGVGNLSG---------------------- 108

  Fly   381 DDSDSG---STDARRKKKARTTFTGRQIFELEKMFENKKYLSASERTEMAKLLMVTETQVKIWFQ 442
             |...|   ||..|.::|:|..|:..|:..||:.|:.::||:|.||..:|..|.:|.||||||||
Mouse   109 -DMRRGGPVSTRTRPQRKSRVLFSQAQVLALERRFKQQRYLTAPEREHLASALQLTSTQVKIWFQ 172

  Fly   443 NRRTKWKKQDNVTNNEAAEHKSS-----------NAKP-----------------------GATG 473
            |||.|.|.|......|.|.|..:           :.||                       |..|
Mouse   173 NRRYKSKSQRQDQTLELAGHPLAPRRVAVPVLVLDGKPCLDPDVAAFLGPYKATSPYSCFGGYAG 237

  Fly   474 T---------ATTTPSGE-PTDKRSSNATSPTVGNAATIAEIKKSPK 510
            |         .|:..:|. |....:|:..||...:||....:..:|:
Mouse   238 TPYDASYASRCTSASAGPGPLTPLASSGFSPGGQSAAPQGHLPATPQ 284

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NK7.1	NP_650357.2	Homeodomain	394..450	CDD:459649	27/55 (49%)
Nkx2-6	NP_035050.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	75..125		16/102 (16%)
		Homeodomain	124..179	CDD:459649	27/54 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	259..289		6/26 (23%)