DRSC/TRiP Functional Genomics Resources

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Protein Alignment NK7.1 and Nkx2-2

DIOPT Version :9

Sequence 1:NP_001247103.1 Gene:NK7.1 / 41747 FlyBaseID:FBgn0024321 Length:721 Species:Drosophila melanogaster
Sequence 2:NP_035049.1 Gene:Nkx2-2 / 18088 MGIID:97347 Length:273 Species:Mus musculus


Alignment Length:268 Identity:70/268 - (26%)
Similarity:99/268 - (36%) Gaps:98/268 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly   191 TPHSIADILGMSFVKKERPEVAFDAQGPAKSPNSILKPYQEQQPIRSSSISMSDASEEESAAVAG 255
            |..|:.|||.:.....|...|   |:||                            ||||.    
Mouse     8 TGFSVKDILDLPDTNDEDGSV---AEGP----------------------------EEESE---- 37

  Fly   256 ATSAATAAAAVAATITAATVATPLDQPLNLCVVKKSRDSNNSP----MPATKQSQI----LGKSA 312
            ....|..|..:......|..:.||..|.        .||:::|    :.:|:..|.    |..||
Mouse    38 GPEPAKRAGPLGQGALDAVQSLPLKSPF--------YDSSDNPYTRWLASTEGLQYSLHGLAASA 94

  Fly   313 TKKESSGKPAAKKKKLSSTVALPPDISPTGSSDSLMRDKLMANNSSSPGSNVNAQMQSNANSTLE 377
            ..::||.|                  ||..|:|            .||.:               
Mouse    95 PPQDSSSK------------------SPEPSAD------------ESPDN--------------- 114

  Fly   378 TTEDDSDSGSTDARRKKKARTTFTGRQIFELEKMFENKKYLSASERTEMAKLLMVTETQVKIWFQ 442
              :.::..|..||.:|:|.|..|:..|.:|||:.|..::||||.||..:|.|:.:|.||||||||
Mouse   115 --DKETQGGGGDAGKKRKRRVLFSKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQ 177

  Fly   443 NRRTKWKK 450
            |.|.|.|:
Mouse   178 NHRYKMKR 185

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
NK7.1NP_001247103.1 Homeobox 397..449 CDD:278475 27/51 (53%)
Nkx2-2NP_035049.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..56 16/82 (20%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 91..131 15/86 (17%)
Homeobox 131..185 CDD:395001 27/53 (51%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167833351
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.840

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