DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment NK7.1 and Msx2

DIOPT Version :10

Sequence 1:NP_650357.2 Gene:NK7.1 / 41747 FlyBaseID:FBgn0024321 Length:721 Species:Drosophila melanogaster
Sequence 2:NP_038629.2 Gene:Msx2 / 17702 MGIID:97169 Length:267 Species:Mus musculus


Alignment Length:211 Identity:67/211 - (31%)
Similarity:91/211 - (43%) Gaps:43/211 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   325 KKKLSSTVALPPDISPTGSSDSLMRDKLM----ANNSSSPGSNVNAQMQSNANSTLETTEDDSD- 384
            ||....:.|:|||.:..|   :::|..|:    ..::.|||..|.....::..|  |.:||.:. 
Mouse    56 KKPPKESPAVPPDCASAG---AVLRPLLLPGHGVRDAHSPGPLVKPFETASVKS--ENSEDGAPW 115

  Fly   385 --------------SGSTDARRK----KKARTTFTGRQIFELEKMFENKKYLSASERTEMAKLLM 431
                          |.:|...||    :|.||.||..|:..||:.|..|:|||.:||.|.:..|.
Mouse   116 IQEPGRYSPPPRHMSPTTCTLRKHKTNRKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSSSLN 180

  Fly   432 VTETQVKIWFQNRRTKWKKQDNVTNNEAAEHKSSNAKPG-ATGTATTTPSGEPTDKRSSNATS-- 493
            :|||||||||||||.|.|:    ......|.....|||. .:|.:...|...|....|....|  
Mouse   181 LTETQVKIWFQNRRAKAKR----LQEAELEKLKMAAKPMLPSGFSLPFPINSPLQAASIYGASYP 241

  Fly   494 --------PTVGNAAT 501
                    |.||..||
Mouse   242 FHRPVLPIPPVGLYAT 257

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
NK7.1NP_650357.2 Homeodomain 394..450 CDD:459649 31/55 (56%)
Msx2NP_038629.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..42
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 104..132 5/29 (17%)
Homeodomain 143..199 CDD:459649 31/55 (56%)
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.