Protein Alignment NK7.1 and DLX6

DIOPT Version :10

• Sequence 1: NP_650357.2
• Gene: NK7.1 / 41747
• FlyBaseID: FBgn0024321
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_005213.3
• Gene: DLX6 / 1750
• HGNCID: 2919
• Length: 293
• Species: Homo sapiens
• Alignment Length: 387
• Identity: 88/387 - (22%)
• Similarity: 129/387 - (33%)
• Gaps: 164/387 - (42%)

  Fly   147 QQPQQQTVQLQQQRRSVSTPAITTTPGPPTNWHAHVYDRLPPHPTPHSIADILGMSFVKKERPEV 211
            ||.|||..|.|||::....|     |.||           ||.|.||
Human    26 QQQQQQQQQQQQQQQQQQQP-----PPPP-----------PPPPQPH------------------ 56

  Fly   212 AFDAQGPAKSPNSILKPYQEQQPIRSSSISMSDASEEESAAVAGA-------TSAATAAAAVAAT 269
                                              |::.|.|:|||       .|||.||||
Human    57 ----------------------------------SQQSSPAMAGAHYPLHCLHSAAAAAAA---- 83

  Fly   270 ITAATVATPLDQPLNLCVVKKSRDSNNSPMPATKQSQILGKSATKKESSGKPAAKKKKLSSTVAL 334
                                .|...::.                :....|.|.|
Human    84 --------------------GSHHHHHH----------------QHHHHGSPYA----------- 101

  Fly   335 PPDISPTGSS---DSLMRDKLMANNSSSPGSNVNAQMQSNANSTLETTEDDSDSGST-------- 388
                |..|:|   .||.....|:::..||    ..|...|:::..:|..||:|...|
Human   102 ----SGGGNSYNHRSLAAYPYMSHSQHSP----YLQSYHNSSAAAQTRGDDTDQQKTTVIENGEI 158

  Fly   389 ----DARRKKKARTTFTGRQIFELEKMFENKKYLSASERTEMAKLLMVTETQVKIWFQNRRTKWK 449
                ..::.:|.||.::..|:..|...|:..:||:..||.|:|..|.:|:|||||||||:|:|:|
Human   159 RFNGKGKKIRKPRTIYSSLQLQALNHRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFK 223

  Fly   450 KQDNVTNNEAAEHKSSNAKPGATGTATTTPSGEPTDKRSSNATSPTVGNAATIAEIKKSPKS 511
            |   :....:..|:|...:    |:|..:|        .|.|..|....:|:...:...|.|
Human   224 K---LLKQGSNPHESDPLQ----GSAALSP--------RSPALPPVWDVSASAKGVSMPPNS 270

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NK7.1	NP_650357.2	Homeodomain	394..450	CDD:459649	25/55 (45%)
DLX6	NP_005213.3	Homeodomain	168..224	CDD:459649	25/55 (45%)