Protein Alignment NK7.1 and DLX5

DIOPT Version :10

• Sequence 1: NP_650357.2
• Gene: NK7.1 / 41747
• FlyBaseID: FBgn0024321
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_005212.1
• Gene: DLX5 / 1749
• HGNCID: 2918
• Length: 289
• Species: Homo sapiens
• Alignment Length: 321
• Identity: 76/321 - (23%)
• Similarity: 117/321 - (36%)
• Gaps: 78/321 - (24%)

  Fly   214 DAQGPAKSPNSILKPYQEQQPIRSSSISMSDASEEESAAVAGATSAATAAAAVAATITAATVATP 278
            |.|.|.::..::..|.||...:..||.:.||.......|..|..|..:|:...|
Human    16 DFQAPFQTSAAMHHPSQESPTLPESSATDSDYYSPTGGAPHGYCSPTSASYGKA----------- 69

  Fly   279 LDQPLNLCVVKKSRDSNNSPMPATKQSQILGKSATKKESSGKPAAKKKKLSSTVALPPDISPTGS 343
                ||                 ..|.|..|.:.    |:|...||
Human    70 ----LN-----------------PYQYQYHGVNG----SAGSYPAK------------------- 90

  Fly   344 SDSLMRDKLMANNSSSPGSNVNAQMQSNANSTLETTEDDSDSGSTDARRKKKARTTFTGRQIFEL 408
               ...|...|::....|...|....:......|.||.:....:...::.:|.||.::..|:..|
Human    91 ---AYADYSYASSYHQYGGAYNRVPSATNQPEKEVTEPEVRMVNGKPKKVRKPRTIYSSFQLAAL 152

  Fly   409 EKMFENKKYLSASERTEMAKLLMVTETQVKIWFQNRRTKWKKQDNVTNNE-AAEHKSSNAKP--- 469
            ::.|:..:||:..||.|:|..|.:|:|||||||||:|:|.||  .:.|.| ..||..|::.|
Human   153 QRRFQKTQYLALPERAELAASLGLTQTQVKIWFQNKRSKIKK--IMKNGEMPPEHSPSSSDPMAC 215

  Fly   470 ------------GATGTATTTPSGEPTDKRSSNATSPTVGNAATIAEIKKSPKS--PNRGS 516
                        |::.:.:..|...|.....|.|:|....:|:.......|..|  |..||
Human   216 NSPQSPAVWEPQGSSRSLSHHPHAHPPTSNQSPASSYLENSASWYTSAASSINSHLPPPGS 276

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NK7.1	NP_650357.2	Homeodomain	394..450	CDD:459649	25/55 (45%)
DLX5	NP_005212.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..49		10/32 (31%)
		DLL_N	32..118	CDD:463567	24/143 (17%)
		Homeodomain	138..194	CDD:459649	25/55 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	198..251		11/52 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	270..289		3/7 (43%)