Protein Alignment NK7.1 and DLX4

DIOPT Version :10

• Sequence 1: NP_650357.2
• Gene: NK7.1 / 41747
• FlyBaseID: FBgn0024321
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_612138.1
• Gene: DLX4 / 1748
• HGNCID: 2917
• Length: 240
• Species: Homo sapiens
• Alignment Length: 267
• Identity: 58/267 - (21%)
• Similarity: 106/267 - (39%)
• Gaps: 71/267 - (26%)

  Fly   277 TPLDQPLNLCVVKKSRDSNN------SPMPATKQSQILGKSATKKESSGKPAAKKKKLSSTVALP 335
            |.|..||      ..||::.      :|:|:...:..||                  ||.|.|..
Human     2 TSLPCPL------PGRDASKAVFPDLAPVPSVAAAYPLG------------------LSPTTAAS 42

  Fly   336 PDIS---------------PTGSSDSLM---RDKLMANNSSSPGSNVNAQMQSNANSTLETTEDD 382
            |::|               |....||.:   :...::.....|..:.. ::::::.....:.|..
Human    43 PNLSYSRPYGHLLSYPYTEPANPGDSYLSCQQPAALSQPLCGPAEHPQ-ELEADSEKPRLSPEPS 106

  Fly   383 SDSGSTDARRKKKARTTFTGRQIFELEKMFENKKYLSASERTEMAKLLMVTETQVKIWFQNRRTK 447
            .......|::.:|.||.::..|:..|.:.|::.:||:..||.::|..|.:|:|||||||||:|:|
Human   107 ERRPQAPAKKLRKPRTIYSSLQLQHLNQRFQHTQYLALPERAQLAAQLGLTQTQVKIWFQNKRSK 171

  Fly   448 WKKQDNVTNNEAAEHKSSNAKPGATGTATTTPSGEPTDKRSSNATSPTVGNAATIAEIKKSPKSP 512
            :||.  :..|...:....   ||.  |.:.:|...|               ..::.::.|:...|
Human   172 YKKL--LKQNSGGQEGDF---PGR--TFSVSPCSPP---------------LPSLWDLPKAGTLP 214

  Fly   513 NRGSNNN 519
            ..|..|:
Human   215 TSGYGNS 221

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NK7.1	NP_650357.2	Homeodomain	394..450	CDD:459649	24/55 (44%)
DLX4	NP_612138.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	80..120		3/40 (8%)
		Homeodomain	118..174	CDD:459649	24/55 (44%)