Protein Alignment NK7.1 and DLX2

DIOPT Version :10

• Sequence 1: NP_650357.2
• Gene: NK7.1 / 41747
• FlyBaseID: FBgn0024321
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_004396.1
• Gene: DLX2 / 1746
• HGNCID: 2915
• Length: 328
• Species: Homo sapiens
• Alignment Length: 312
• Identity: 76/312 - (24%)
• Similarity: 118/312 - (37%)
• Gaps: 84/312 - (26%)

  Fly   229 YQEQQP----------IRSSSISMSDASEEESAAVAGATSAA-------TAAAAVAATITAATVA 276
            :|.|||          ..|||.|:....|..:..|:.||.::       .|..........|.:.
Human    24 HQHQQPPSGGGAGPGGNSSSSSSLHKPQESPTLPVSTATDSSYYTNQQHPAGGGGGGGSPYAHMG 88

  Fly   277 TPLDQPLNLCVVKKSRDSNNSPMPATKQSQILGKSATKKESSGKPAAKKKKLSSTVALPPDISPT 341
            :...|...|         ||.|..| |.|..||.:|..                     ...:|.
Human    89 SYQYQASGL---------NNVPYSA-KSSYDLGYTAAY---------------------TSYAPY 122

  Fly   342 GSSDSLMRDKLMANNSSSPGSNVNAQMQSNANSTLETTEDDSDSGSTDARRKK--KARTTFTGRQ 404
            |:             ||||           ||:..|..:.:.:....:.:.||  |.||.::..|
Human   123 GT-------------SSSP-----------ANNEPEKEDLEPEIRIVNGKPKKVRKPRTIYSSFQ 163

  Fly   405 IFELEKMFENKKYLSASERTEMAKLLMVTETQVKIWFQNRRTKWKKQDNVTNNEAAEHKSSNAKP 469
            :..|::.|:..:||:..||.|:|..|.:|:|||||||||||:|:||........:.:|..::|.|
Human   164 LAALQRRFQKTQYLALPERAELAASLGLTQTQVKIWFQNRRSKFKKMWKSGEIPSEQHPGASASP 228

  Fly   470 GATGTATTTPS----GEPTDKRSSNATSPTVGNAATIAEIKKSPKSPNRGSN 517
            .......:.|:    |.|  :|.:....|..|.:..    ..|..||:..::
Human   229 PCASPPVSAPASWDFGVP--QRMAGGGGPGSGGSGA----GSSGSSPSSAAS 274

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NK7.1	NP_650357.2	Homeodomain	394..450	CDD:459649	27/57 (47%)
DLX2	NP_004396.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	16..81		13/56 (23%)
		DLL_N	51..132	CDD:463567	25/135 (19%)
		Homeodomain	153..209	CDD:459649	26/55 (47%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	211..270		11/64 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	300..328