Protein Alignment NK7.1 and NKX6-3

DIOPT Version :10

• Sequence 1: NP_650357.2
• Gene: NK7.1 / 41747
• FlyBaseID: FBgn0024321
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_001351770.1
• Gene: NKX6-3 / 157848
• HGNCID: 26328
• Length: 265
• Species: Homo sapiens
• Alignment Length: 211
• Identity: 70/211 - (33%)
• Similarity: 89/211 - (42%)
• Gaps: 56/211 - (26%)

  Fly   327 KLSSTVALPPDI-------SPTGSSDSLMRDKLMANNS--------------SSPGSNVNAQMQS 370
            |||     ||.:       :|.|.:|.|.|.....|||              ||.|...:.|:.:
Human    37 KLS-----PPGLGPQLAAGTPHGITDILSRPVAAPNNSLLSGYPHVAGFGGLSSQGVYYSPQVGN 96

  Fly   371 -----------NANSTLETTED---------DSDSGSTDARRKKKARTTFTGRQIFELEKMFENK 415
                       ..|...:|.:|         ..|..|....:||..|.||||.|||.|||.||..
Human    97 FSKAGNEYPTRTRNCWADTGQDWRGGRQCSNTPDPLSDSIHKKKHTRPTFTGHQIFALEKTFEQT 161

  Fly   416 KYLSASERTEMAKLLMVTETQVKIWFQNRRTKWKKQDNVTNNEAAEHKSSNAKPGATGTATTTPS 480
            |||:..||..:|..|.:||:|||:|||||||||:|:      .|.|..||.  |.|.|.|.....
Human   162 KYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKK------SALEPSSST--PRAPGGAGAGAG 218

  Fly   481 GE--PTDKRSSNATSP 494
            |:  |::........|
Human   219 GDRAPSENEDDEYNKP 234

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NK7.1	NP_650357.2	Homeodomain	394..450	CDD:459649	35/55 (64%)
NKX6-3	NP_001351770.1	Homeodomain	138..196	CDD:459649	36/57 (63%)