Protein Alignment NK7.1 and Hmx1

DIOPT Version :10

• Sequence 1: NP_650357.2
• Gene: NK7.1 / 41747
• FlyBaseID: FBgn0024321
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_034575.1
• Gene: Hmx1 / 15371
• MGIID: 107178
• Length: 332
• Species: Mus musculus
• Alignment Length: 382
• Identity: 86/382 - (22%)
• Similarity: 124/382 - (32%)
• Gaps: 146/382 - (38%)

  Fly   144 PQHQQPQQ--QTVQLQQQRRSVSTP-------AITTTPGPPTNWHAHVYDRLPPHPTPHSIADIL 199
            |:.:.|:|  :.:|.::|:|:.|.|       |:...|.|            ||.|.|   ...|
Mouse    52 PEDEDPEQARRRLQRRRQQRAGSGPGGEARARALGLGPRP------------PPGPGP---PFAL 101

  Fly   200 GMSFVKKERPEVAFDAQGPAKSPNSILKPYQEQQPIRSSSISMSDASEEESAAVAGATSAATAAA 264
            |.....:..|.| ....|...||::                  ||....|:....|...:|....
Mouse   102 GCGGTTRWYPRV-HGGYGGGLSPDT------------------SDRDSPETGEEMGRAESAWPRC 147

  Fly   265 AVAATITAATVATPLDQPLNLCVVKKSRDSNNSPMPATKQSQILGKSATKKESSGKPAAKKKKLS 329
            ....|:                           |...|.|....|         |:.||:..:..
Mouse   148 PGPGTV---------------------------PREVTTQGPATG---------GEEAAELAEAP 176

  Fly   330 STVALPPDISPTGSSDSLMRDKLMANNSSSPGSNVNAQMQSNANSTLETTEDDSDSGSTDARRKK 394
            :..|                                                 :.:|.....|:|
Mouse   177 AVAA-------------------------------------------------AATGEARGGRRK 192

  Fly   395 KARTTFTGRQIFELEKMFENKKYLSASERTEMAKLLMVTETQVKIWFQNRRTKWKKQDNVTNNEA 459
            |.||.|:..|:|:||..|:.|:|||::||..:|..|.:|||||||||||||.|||:| .....||
Mouse   193 KTRTVFSRSQVFQLESTFDLKRYLSSAERAGLAASLQLTETQVKIWFQNRRNKWKRQ-LAAELEA 256

  Fly   460 AEHKSSNAK-------------PGATGTATTTPSGEPTDKRSSNATSPTVGNAATIA 503
            |......|:             |.|.|.|...|...|    :.....|.:|.:..:|
Mouse   257 ASLSPPGAQRLVRVPVLYHESPPAAAGPALPFPLAPP----APAPPPPLLGFSGALA 309

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NK7.1	NP_650357.2	Homeodomain	394..450	CDD:459649	33/55 (60%)
Hmx1	NP_034575.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	28..170		33/187 (18%)
		Homeodomain	192..248	CDD:459649	33/55 (60%)
		HMX family specific domain 1	251..261		3/9 (33%)
		HMX family specific domain 2	264..277		1/12 (8%)