Protein Alignment NK7.1 and Hlx

DIOPT Version :10

• Sequence 1: NP_650357.2
• Gene: NK7.1 / 41747
• FlyBaseID: FBgn0024321
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_032276.1
• Gene: Hlx / 15284
• MGIID: 96109
• Length: 476
• Species: Mus musculus
• Alignment Length: 488
• Identity: 102/488 - (20%)
• Similarity: 175/488 - (35%)
• Gaps: 152/488 - (31%)

  Fly   164 STPAITTTPG---PPTNWHAHVYDRLPPHPTPHSIADILGMSFVKKERP-EVAFDAQGPAKSPNS 224
            ::.|:|...|   |..::.|..  |.|..|||......:...|.::..| ..||....|.:||..
Mouse    67 ASAALTAHLGSVHPHASFQAAA--RSPLRPTPVVAPSEVPAGFPQRLSPLSAAFHQHLPQQSPTQ 129

  Fly   225 ILKPYQEQQPIRSSSISMSDASEEESAAVAGATSAATAAAAVAATITAATVATPLDQPLNLCVVK 289
            ..:| |:|.|....::|:...                         |:.|...|
Mouse   130 QQQP-QQQPPPPPRAVSLQPP-------------------------TSGTRVVP----------- 157

  Fly   290 KSRDSNNSPMPATKQ-----SQILG-------------KSATKKESSGKPAAKKKKLSSTVALPP 336
              ..|.::|.|::|.     .:||.             :..|...:.|:||.     .....|.|
Mouse   158 --HHSGSAPAPSSKDLKFGIDRILSAEFDPKVKEGNTLRDLTSLLTGGRPAG-----VHLAGLQP 215

  Fly   337 -------DISPTGSSDSLMRDKLMANNSSSPGSNVNAQMQSNANSTLETTEDDSDSGSTDARRKK 394
                   .:.|...:.:     :::..||:|.::|..|.|............|: ...|..|::.
Mouse   216 SAGQFFASLDPISEASA-----ILSPLSSNPRNSVQHQFQDTFPGPYAVLTKDT-MPQTYKRKRS 274

  Fly   395 KARTTFTGRQIFELEKMFENKKYLSASERTEMAKLLMVTETQVKIWFQNRRTKWKKQDNVTNNEA 459
            .:|..|:..|...|||.||.:||::..:|.::|.:|.:|:.|||:||||||.||:.     :.||
Mouse   275 WSRAVFSNLQRKGLEKRFEIQKYVTKPDRKQLAAMLGLTDAQVKVWFQNRRMKWRH-----SKEA 334

  Fly   460 AEHKSSNAKPGATGTATTTPSGEPTDKRSSNATSPTVGNAATIAEIKKSPKSPNRG-----SNNN 519
            ...|..:.:.|      ..|||                  ...||.::..:||:|.     |.::
Mouse   335 QAQKDKDKEAG------EKPSG------------------GVPAEGEREERSPSRSEGEAESESS 375

  Fly   520 NNNTLN---NNVNNSEGKVPAKQSTTKIK-KQLNALLEKTVKTAN-------------------- 560
            ::.:|:   ::...:||...:...||.|| ....||:..:..|:.
Mouse   376 DSESLDMAPSDTERTEGTERSLHQTTVIKASAAGALITASSSTSGSSFSFSSTSSLGSGNTHVGS 440

  Fly   561 ------------QAHRSAELESSDQKPAVEKRP 581
                        .||:.: :.||.|.|.:.:.|
Mouse   441 ASSLGGNCSELPSAHQPS-VTSSPQSPEIAQAP 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NK7.1	NP_650357.2	Homeodomain	394..450	CDD:459649	25/55 (45%)
Hlx	NP_032276.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	120..169		14/87 (16%)
		Homeodomain	270..330	CDD:459649	26/59 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	328..401		17/101 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	413..476		8/61 (13%)