DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment NK7.1 and Gbx2

DIOPT Version :9

Sequence 1:NP_001247103.1 Gene:NK7.1 / 41747 FlyBaseID:FBgn0024321 Length:721 Species:Drosophila melanogaster
Sequence 2:NP_034392.1 Gene:Gbx2 / 14472 MGIID:95668 Length:348 Species:Mus musculus


Alignment Length:369 Identity:97/369 - (26%)
Similarity:136/369 - (36%) Gaps:115/369 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly   122 PPTTFLQKQLEAVVAPRPSSVHPQHQQPQQQT--VQLQQQRRSVSTPAITTTPG----PPTNWHA 180
            ||....|..|:..:.|    .||.||.|...|  .....|..::::..:.|.||    .|.:..|
Mouse    61 PPPALPQAALQPALPP----AHPHHQIPSLPTGFCSSLAQGMALTSTLMATLPGGFSASPQHQEA 121

  Fly   181 HVYDRLPPHPTPHSIADILGMSFVKKERPEVAFDAQGPAKSPNSILKPYQEQQPIRSSSISMSDA 245
            ....:..|.|.|.      |.:|.|.|.      .|..|:...:.|                   
Mouse   122 AAARKFAPQPLPG------GGNFDKAEA------LQADAEDGKAFL------------------- 155

  Fly   246 SEEESAAVAGATSAATAAAAVAATITAATVATPLDQPLNLCVVKKSRDSNNSPMPATKQSQILGK 310
                  |..|:..|.:||.||.|::..|.                             :.|  ||
Mouse   156 ------AKEGSLLAFSAAEAVQASLVGAV-----------------------------RGQ--GK 183

  Fly   311 SATKKESSGKPAAKKKKLSSTVALPPDISPTGSSDSLMRDKLMANNSSSPGSNVNAQMQSNANST 375
            ..:|.|...|...:...|.|.|    |.|   |.|:|            ||...:.: :...::.
Mouse   184 DESKVEDDPKGKEESFSLESDV----DYS---SDDNL------------PGQTAHKE-EDPGHAL 228

  Fly   376 LETTEDDSDSGSTDARRK-KKARTTFTGRQIFELEKMFENKKYLSASERTEMAKLLMVTETQVKI 439
            .||.:....:|||.:..| ::.||.||..|:.||||.|..|||||.:||:::|..|.::|.||||
Mouse   229 EETPQSGGAAGSTTSTGKNRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKI 293

  Fly   440 WFQNRRTKWKKQDNVTNNEAAEHKSSNAKPGATGTATTTPSGEP 483
            ||||||.|||:                .|.|...:.|..||..|
Mouse   294 WFQNRRAKWKR----------------VKAGNANSKTGEPSRNP 321

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
NK7.1NP_001247103.1 Homeobox 397..449 CDD:278475 31/51 (61%)
Gbx2NP_034392.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 59..81 7/23 (30%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 111..139 6/33 (18%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 179..251 22/93 (24%)
Homeobox 250..304 CDD:395001 32/53 (60%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.910

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