Protein Alignment NK7.1 and En1

DIOPT Version :10

• Sequence 1: NP_650357.2
• Gene: NK7.1 / 41747
• FlyBaseID: FBgn0024321
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_034263.2
• Gene: En1 / 13798
• MGIID: 95389
• Length: 401
• Species: Mus musculus
• Alignment Length: 430
• Identity: 107/430 - (24%)
• Similarity: 154/430 - (35%)
• Gaps: 134/430 - (31%)

  Fly   131 LEAVVAPRPS----SVHP---QHQQPQQQTVQLQQQRRSVSTPAITTTPGPPTNWHAHVYDRLPP 188
            |.||.|..||    |:.|   ........:|.:..|....|.||....  ||...|.|    |||
Mouse    16 LGAVAAAAPSGLSLSLSPGASGSSGSDGDSVPVSPQPAPPSPPAAPCL--PPLAHHPH----LPP 74

  Fly   189 HPTP----------------HS--------------IADILGMSF-VKKERP----EVAFDAQGP 218
            ||.|                |.              |.:||...| .|||:|    .||..|.|.
Mouse    75 HPPPPPPPPPPPPQHLAAPAHQPQPAAQLHRTTNFFIDNILRPDFGCKKEQPLPQLLVASAAAGG 139

  Fly   219 AKSPNSILKPYQE-------QQPIRSSSISMS----------------DASEEESAAVAGAT--- 257
            ..:.....:..::       :.|:.|.....|                |.|:..:|..|||:
Mouse   140 GAAAGGGSRVERDRGQTGAGRDPVHSLGTRASGAASLLCAPDANCGPPDGSQPATAVSAGASKAG 204

  Fly   258 ----SAATAAAAVAATITAATVATPLDQPLNLCVVKKSRDSNNSPMPATKQSQILGKSATKKESS 318
                :||.||||.||.:.||..|                        |:|.|...|.|.   .::
Mouse   205 NPAAAAAAAAAAAAAAVAAAAAA------------------------ASKPSDSGGGSG---GNA 242

  Fly   319 GKPAAKKKKLSSTVALPPDISPTGSSDSLMRDKLMANNSSSPGSNVNAQMQSNANSTLETT--ED 381
            |.|.|:..|.       |:.:|     :::   ||.:.:..|....::|......:.:..|  .|
Mouse   243 GSPGAQGAKF-------PEHNP-----AIL---LMGSANGGPVVKTDSQQPLVWPAWVYCTRYSD 292

  Fly   382 DSDSGSTDARRKKK--------ARTTFTGRQIFELEKMFENKKYLSASERTEMAKLLMVTETQVK 438
            ...||....:.|||        .||.||..|:..|:..|:..:|::...|..:|:.|.:.|:|:|
Mouse   293 RPSSGPRTRKLKKKKNEKEDKRPRTAFTAEQLQRLKAEFQANRYITEQRRQTLAQELSLNESQIK 357

  Fly   439 IWFQNRRTKWKKQDNVTNNEAAEHKSSNAKPGATGTATTT 478
            |||||:|.|.||...:.|..|....:.    |....:|||
Mouse   358 IWFQNKRAKIKKATGIKNGLALHLMAQ----GLYNHSTTT 393

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NK7.1	NP_650357.2	Homeodomain	394..450	CDD:459649	23/63 (37%)
En1	NP_034263.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..102		24/91 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	138..167		3/28 (11%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	229..253		8/33 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	293..315		5/21 (24%)
		Homeodomain	314..369	CDD:459649	21/54 (39%)
		Engrail_1_C_sig	370..400	CDD:431338	6/28 (21%)