Protein Alignment NK7.1 and NKX2-6

DIOPT Version :9

• Sequence 1: NP_001247103.1
• Gene: NK7.1 / 41747
• FlyBaseID: FBgn0024321
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_001129743.2
• Gene: NKX2-6 / 137814
• HGNCID: 32940
• Length: 301
• Species: Homo sapiens
• Alignment Length: 304
• Identity: 76/304 - (25%)
• Similarity: 110/304 - (36%)
• Gaps: 96/304 - (31%)

  Fly   187 PPHPTPHSIADILGMSFVKKERPEVAFDAQGPAKSPNSILKPYQEQQPIRSSSISMSDA----SE 247
            |...||.|:.|||.:   ::||       ..||.||:    |...:.|.....:.| ||    ||
Human     5 PVTSTPFSVKDILRL---ERER-------SCPAASPH----PRVRKSPENFQYLRM-DAEPRGSE 54

  Fly   248 EESAAVAGATSAATAAAAVAATITAATVATPLDQPLNLCVVKKSRDSNNSPMPATKQSQILGKSA 312
            ..:|...|.                                  .|..:.|..|......:|...|
Human    55 VHNAGGGGG----------------------------------DRKLDGSEPPGGPCEAVLEMDA 85

  Fly   313 TKKESSGKPAAKKKKLSSTVALPPDISPTGSSDSLMRDKLMANNSSSP---GSNVNAQMQSNANS 374
               |..|:|             .|.:                 |::||   |:.|..:...|:..
Human    86 ---ERMGEP-------------QPGL-----------------NAASPLGGGTRVPERGVGNSGD 117

  Fly   375 TLETTEDDSDSGSTDARRKKKARTTFTGRQIFELEKMFENKKYLSASERTEMAKLLMVTETQVKI 439
            ::.    ...|....||:::|.|..|:..|:..||:.|:.::||||.||..:|..|.:|.|||||
Human   118 SVR----GGRSEQPKARQRRKPRVLFSQAQVLALERRFKQQRYLSAPEREHLASALQLTSTQVKI 178

  Fly   440 WFQNRRTKWKKQDNVTNNEAAEHKSSNAKPGATGTATTTPSGEP 483
            ||||||.|.|:|....:.|.|.|..:   |...........|:|
Human   179 WFQNRRYKCKRQRQDKSLELAGHPLT---PRRVAVPVLVRDGKP 219

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NK7.1	NP_001247103.1	Homeobox	397..449	CDD:278475	27/51 (53%)
NKX2-6	NP_001129743.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	22..135		33/195 (17%)
		HOX	132..188	CDD:197696	28/55 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143193
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840