Protein Alignment NK7.1 and Nkx2-5

DIOPT Version :10

• Sequence 1: NP_650357.2
• Gene: NK7.1 / 41747
• FlyBaseID: FBgn0024321
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_446103.2
• Gene: Nkx2-5 / 114109
• RGDID: 620520
• Length: 319
• Species: Rattus norvegicus
• Alignment Length: 366
• Identity: 85/366 - (23%)
• Similarity: 125/366 - (34%)
• Gaps: 116/366 - (31%)

  Fly   188 PHP----TPHSIADILGMSFVKKERPEVAFDAQ-------GPAKSPNSILKPYQEQQPIRSSSIS 241
            |.|    ||.|:.|||.:.  :::|...|.|..       .||....:..||
  Rat     3 PSPALTHTPFSVKDILNLE--QQQRSLAAGDLSARLEATLAPASCMLAAFKP------------- 52

  Fly   242 MSDASEEESAAVAGATSAATAAAAVAATITAATVATPLDQPLNLCVVKKSRDSNNSPMPATKQSQ 306
                     .|.:|..:||...|.:.|.:      .|...|        .:.|...|...|...:
  Rat    53 ---------EAYSGPEAAAPGLAELRAEL------GPAPSP--------PKCSPAFPTAPTFYPR 94

  Fly   307 ILGKSATKKESSGKPAAKKKKLSSTVALPPDISPTGSSDSLMRDKLMANNSSSPGSNVNAQMQSN 371
            ..|.....|:    |.|.||:|.:.            ..::..||...:.:..|
  Rat    95 AYGDPDPAKD----PRADKKELCAL------------QKAVELDKAETDGAERP----------- 132

  Fly   372 ANSTLETTEDDSDSGSTDARRKKKARTTFTGRQIFELEKMFENKKYLSASERTEMAKLLMVTETQ 436
                             .|||::|.|..|:..|::|||:.|:.::||||.||.::|.:|.:|.||
  Rat   133 -----------------RARRRRKPRVLFSQAQVYELERRFKQQRYLSAPERDQLASVLKLTSTQ 180

  Fly   437 VKIWFQNRRTKWKKQDNVTNNE------------AAEHKSSNAKPGATGTATTTP---------- 479
            |||||||||.|.|:|......|            |......:.||....:|...|
  Rat   181 VKIWFQNRRYKCKRQRQDQTLELLGPPPPPARRIAVPVLVRDGKPCLGDSAAYAPAYGVGLNAYG 245

  Fly   480 -SGEPTDKRSSNATSPTVGNAATIAEIKKSPKSPNRGSNNN 519
             :..|.......|.||....||.......:.:.|...:|:|
  Rat   246 YNAYPYPGYGGAACSPAYSCAAAYPAAPPAAQPPAAAANSN 286

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NK7.1	NP_650357.2	Homeodomain	394..450	CDD:459649	29/55 (53%)
Nkx2-5	NP_446103.2	Homeodomain	144..194	CDD:459649	27/49 (55%)