Protein Alignment NK7.1 and CDX2

DIOPT Version :10

• Sequence 1: NP_650357.2
• Gene: NK7.1 / 41747
• FlyBaseID: FBgn0024321
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: XP_011533177.1
• Gene: CDX2 / 1045
• HGNCID: 1806
• Length: 321
• Species: Homo sapiens
• Alignment Length: 263
• Identity: 67/263 - (25%)
• Similarity: 94/263 - (35%)
• Gaps: 60/263 - (22%)

  Fly   262 AAAAVAATITAATVATP-----LDQPLNLCVVKKSRDSNNSPMPATKQSQILGKSATKKE----- 316
            ||||.||.:.:|....|     ...||        |:..|...|.       |.:|....
Human    47 AAAAAAANLDSAQSPGPSWPAAYGAPL--------REDWNGYAPG-------GAAAAANAVAHGL 96

  Fly   317 SSGKPAAKKKKLSSTVALPPDISP----------TGSSDSLMRDKLMANNSSSPG---------- 361
            :.|.|||     :...:.|.|..|          ..::.|.....|...|...||
Human    97 NGGSPAA-----AMGYSSPADYHPHHHPHHHPHHPAAAPSCASGLLQTLNPGPPGPAATAAAEQL 156

  Fly   362 ------SNVNAQMQSNANSTLETTEDDSDSGSTDARRKKKARTTFTGRQIFELEKMFENKKYLSA 420
                  .|:...|:..|..:|.:....|.|.:...|.|.|.|..:|..|..||||.|...:|::.
Human   157 SPGGQRRNLCEWMRKPAQQSLGSQALTSPSSTVKTRTKDKYRVVYTDHQRLELEKEFHYSRYITI 221

  Fly   421 SERTEMAKLLMVTETQVKIWFQNRRTKWKKQDNVTNNEAAEHKSSNAKPGATGTATTTPSGEPTD 485
            ..:.|:|..|.::|.||||||||||.|.:|    .|.:..:.:.....|.........|..:|..
Human   222 RRKAELAATLGLSERQVKIWFQNRRAKERK----INKKKLQQQQQQQPPQPPPPPPQPPQPQPGP 282

  Fly   486 KRS 488
            .||
Human   283 LRS 285

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NK7.1	NP_650357.2	Homeodomain	394..450	CDD:459649	25/55 (45%)
CDX2	XP_011533177.1	Caudal_act	13..179	CDD:461413	31/151 (21%)
		Homeodomain	196..251	CDD:459649	25/54 (46%)