DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment spn-B and rad51

DIOPT Version :9

Sequence 1:	NP_476740.1	Gene:	spn-B / 41746	FlyBaseID:	FBgn0003480	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_998371.2	Gene:	rad51 / 406487	ZFINID:	ZDB-GENE-040426-2286	Length:	340	Species:	Danio rerio

Alignment Length:	256	Identity:	81/256 - (31%)
Similarity:	117/256 - (45%)	Gaps:	41/256 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    87 RVSFGCSALDRCTGGGVVTRGITELCGAAGVGKTQLLLQLSLCVQLPRELGGLGKGVA-YICTES 150
            ::|.|...||:...||:.|..|||:.|....|||||...|::..|||.:.|| |:|.| ||.||.
Zfish   102 QISTGSKELDKLLQGGIETGSITEMFGEFRTGKTQLCHTLAVTCQLPIDQGG-GEGKAMYIDTEG 165

  Fly   151 SFPARRLLQMSKACEKRHPEMELNFLGNI-----FVENHIEAEPLLACVINRIPRLMQQHGIGLI 210
            :|...|||    |..:|:..:..:.|.|:     |..:|      ...::.:...:|.:....|:
Zfish   166 TFRPERLL----AVAERYGLVGSDVLDNVAYARAFNTDH------QTQLLYQASAMMTESRYALL 220

  Fly   211 IIDSVAAIFRLYNDYLERAR------HMRRLADALLSYADKYNCAVVCVNQVATR-DG------Q 262
            |:||..|::|  .||..|..      |:.|....||..||::..|||..|||..: ||      .
Zfish   221 IVDSATALYR--TDYSGRGELSARQGHLGRFLRMLLRLADEFGVAVVITNQVVAQVDGAAMFSAD 283

  Fly   263 DEIPCLGLQWAHLGRTRLRVSRVPKQHRMGDQLITVRKLEILYSPETPNDFAEFLITAEGV 323
            .:.|..|...||...|||.:.:...:.|:         .:|..||..|...|.|.|.|:||
Zfish   284 PKKPIGGNILAHASTTRLYLRKGRGETRI---------CKIYDSPCLPEAEAMFAINADGV 335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
spn-B	NP_476740.1	Rad51	87..323	CDD:285604	79/254 (31%)
spn-B	NP_476740.1	Rad51_DMC1_radA	88..324	CDD:238543	81/255 (32%)
rad51	NP_998371.2	recomb_RAD51	26..340	CDD:274048	81/256 (32%)
		HHH_5	32..81	CDD:291205
		Rad51_DMC1_radA	103..336	CDD:238543	81/255 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0468
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810